Results 61 to 70 of about 11,463 (183)

Free energy profile for unwrapping outer superhelical turn of CENP-A nucleosome

open access: yesBiophysics and Physicobiology, 2019
Eukaryotic genome is packaged in a nucleus in the form of chromatin. The fundamental structural unit of the chromatin is the protein-DNA complex, nucleosome, where DNA of about 150 bp is wrapped around a histone core almost twice.
Hidetoshi Kono   +2 more
doaj   +1 more source

A novel Porphyromonas gingivalis enzyme: An atypical dipeptidyl peptidase III with an ARM repeat domain. [PDF]

open access: yesPLoS ONE, 2017
Porphyromonas gingivalis, an asaccharolytic Gram-negative oral anaerobe, is a major pathogen associated with adult periodontitis, a chronic infective disease that a significant percentage of the human population suffers from.
Altijana Hromić-Jahjefendić   +11 more
doaj   +1 more source

3D Printing of Conducting Polymer Hydrogels for Electrostimulation‐Assisted Tissue Engineering

open access: yesAdvanced Materials, Volume 37, Issue 36, September 11, 2025.
This review highlights nanosized inherently conducting polymers (ICPs) as promising ink constituents for 3D printing of conducting hydrogel (CH)‐based electrostimulation (ES) devices. ICP‐based ink formulation, 3D printing, and solidification strategies are discussed, along with the application of 3D‐printed ICP‐based CHs as ES platforms for regulating
Chien Minh Tran   +6 more
wiley   +1 more source

Divergent RNA transcription:A role in promoter unwinding? [PDF]

open access: yes, 2013
New approaches using biotinylated-psoralen as a probe for investigating DNA structure have revealed new insights into the relationship between DNA supercoiling, transcription and chromatin compaction.
Corless, Samuel   +2 more
core   +1 more source

Unpaired bases in superhelical DNA: kinetic evidence [PDF]

open access: yesNucleic Acids Research, 1974
Kinetic analysis of the early, fast reaction of superhelical DNA with formaldehyde reveals that this region or regions is 56% "single strand like" in character. Hydrogen-tritium exchange studies coupled with other considerations show that this reaction is not due to a difference in conformational motility between form I and form II molecules, but is ...
R J, Jacob, J, Lebowitz, M P, Printz
openaire   +2 more sources

Insights Into the Conformational Dynamics of the Cytoplasmic Domain of Metal‐Sensing Sensor Histidine Kinase ZraS

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 93, Issue 9, Page 1465-1480, September 2025.
ABSTRACT ZraS is a metal sensor integral to ZraPSR, a two‐component signaling system found in enterobacters. It belongs to a family of bifunctional sensor histidine kinases (SHKs) and is speculated to sense zinc‐induced stress on the bacterial envelope.
Nilima Mahapatra   +3 more
wiley   +1 more source

Circularly polarized luminescence from supramolecular assemblies based on small molecules

open access: yesSmart Molecules, Volume 3, Issue 3, September 2025.
This minireview outlines the recent advances of circularly polarized luminescence (CPL)‐active supramolecular assemblies based on small molecules. It covers fundamental concepts of CPL, typical design strategies of CPL‐active materials—including the assembly of chiral luminophores, the assembly of chiral components and achiral luminophores, and the ...
Xinyu Liu   +5 more
wiley   +1 more source

Hopping into a hot seat: Role of DNA structural features on IS5-mediated gene activation and inactivation under stress. [PDF]

open access: yesPLoS ONE, 2017
Insertion sequence elements (IS elements) are proposed to play major roles in shaping the genetic and phenotypic landscapes of prokaryotic cells. Recent evidence has raised the possibility that environmental stress conditions increase IS hopping into new
M Zafri Humayun   +4 more
doaj   +1 more source

Interference between Triplex and Protein Binding to Distal Sites on Supercoiled DNA [PDF]

open access: yes, 2017
We have explored the interdependence of the binding of a DNA triplex and a repressor protein to distal recognition sites on supercoiled DNA minicircles using MD simulations.
Aggarwal   +57 more
core   +2 more sources

The relaxation time for a cruciform structure in superhelical DNA

open access: yesFEBS Letters, 1983
We have calculated the relaxation time of a cruciform structure in superhelical DNA as a function of the superhelix density for palindromic regions of different lengths. The relaxation time has a sharp maximum at the superhelix density which corresponds to the equilibrium transition point between the cruciform structure and the regular double helix ...
Vologodskii, A.V.   +1 more
openaire   +2 more sources

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