Results 41 to 50 of about 11,225 (206)

Specific DNA-RNA Hybrid Recognition by TAL Effectors

open access: yesCell Reports, 2012
The transcription activator-like (TAL) effector targets specific host promoter through its central DNA-binding domain, which comprises multiple tandem repeats (TALE repeats).
Ping Yin   +6 more
doaj   +1 more source

Inferring coarse-grain histone-DNA interaction potentials from high-resolution structures of the nucleosome

open access: yes, 2014
The histone-DNA interaction in the nucleosome is a fundamental mechanism of genomic compaction and regulation, which remains largely unkown despite a growing structural knowledge of the complex.
Everaers, Ralf, Meyer, Sam
core   +3 more sources

Differential influence of DNA supercoiling on in vivo strength of promoters varying in structure and organisation in E. coli [PDF]

open access: yes, 1994
DNA supercoiling is known to influence promoter activity in vitro and in vivo in a promoter-dependent manner in prokaryotes. In order to investigate how topology may influence promoter function, we have studied two kinds of promoter variants, (i) where ...
Jyothirmai, G., Mishra, Rakesh K.
core   +7 more sources

Stress-induced duplex destabilization (SIDD) profiles for T7 bacteriophage promoters [PDF]

open access: yesКомпьютерные исследования и моделирование, 2018
The functioning of DNA regulatory regions rely primarily on their physicochemical and structural properties but not on nucleotide sequences, i.e. genetic text.
Mikhail Anatolievich Orlov   +4 more
doaj   +1 more source

Role of the Discriminator Sequence in the Supercoiling Sensitivity of Bacterial Promoters

open access: yesmSystems, 2021
DNA supercoiling acts as a global transcriptional regulator that contributes to the rapid transcriptional response of bacteria to many environmental changes.
Raphaël Forquet   +4 more
doaj   +1 more source

Contributions of supercoiling to Tn3 resolvase and phage Mu Gin site-specific recombination [PDF]

open access: yes, 1996
Members of the resolvase/invertase family of site-specific recombinases require supercoiled substrates containing two recombination sites. To dissect the roles of supercoiling in recombination by the Tn3 and γδ resolvases and the phage Mu Gin invertase ...
Abola, M.T.B.   +3 more
core   +2 more sources

Characterization of nuclear structures containing superhelical DNA

open access: yesJournal of Cell Science, 1976
ABSTRACT Structures resembling nuclei but depleted of protein may be released by gently lysing cells in solutions containing non-ionic detergents and high concentrations of salt. These nucleoids sediment in gradients containing intercalating agents in a manner characteristic of DNA that is intact, supercoiled and circular.
Cook, P, Brazell, I, Jost, E
openaire   +3 more sources

Spontaneous formation of liquid crystalline phases and phase transitions in highly concentrated plasmid DNA [PDF]

open access: yes, 2011
The liquid crystalline (LC) properties of two supercoiled plasmid DNA samples, pBSK (2958 bp) and pGEM (3000 bp), have been studied using polarised light microscopy (PLM), circular dichroism (CD) and UV-Vis spectroscopy.
Buckle, M.   +5 more
core   +2 more sources

Pentatricopeptide repeat proteins in crops: Advances in functional mechanisms and breeding applications

open access: yesJournal of Integrative Plant Biology, EarlyView.
Pentatricopeptide repeat proteins coordinate nucleus‐organelle communication by modulating RNA metabolism within chloroplasts and mitochondria. This review highlights how they control critical processes like photosynthesis, seed development, fertility restoration, and stress survival in crops, and explores their potential as programmable tools for RNA ...
Mingming Wu   +7 more
wiley   +1 more source

Mechanical response of plectonemic DNA: an analytical solution

open access: yes, 2008
We consider an elastic rod model for twisted DNA in the plectonemic regime. The molecule is treated as an impenetrable tube with an effective, adjustable radius.
Allemand J. F.   +31 more
core   +2 more sources

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