Results 41 to 50 of about 11,225 (206)
Specific DNA-RNA Hybrid Recognition by TAL Effectors
The transcription activator-like (TAL) effector targets specific host promoter through its central DNA-binding domain, which comprises multiple tandem repeats (TALE repeats).
Ping Yin +6 more
doaj +1 more source
The histone-DNA interaction in the nucleosome is a fundamental mechanism of genomic compaction and regulation, which remains largely unkown despite a growing structural knowledge of the complex.
Everaers, Ralf, Meyer, Sam
core +3 more sources
Differential influence of DNA supercoiling on in vivo strength of promoters varying in structure and organisation in E. coli [PDF]
DNA supercoiling is known to influence promoter activity in vitro and in vivo in a promoter-dependent manner in prokaryotes. In order to investigate how topology may influence promoter function, we have studied two kinds of promoter variants, (i) where ...
Jyothirmai, G., Mishra, Rakesh K.
core +7 more sources
Stress-induced duplex destabilization (SIDD) profiles for T7 bacteriophage promoters [PDF]
The functioning of DNA regulatory regions rely primarily on their physicochemical and structural properties but not on nucleotide sequences, i.e. genetic text.
Mikhail Anatolievich Orlov +4 more
doaj +1 more source
Role of the Discriminator Sequence in the Supercoiling Sensitivity of Bacterial Promoters
DNA supercoiling acts as a global transcriptional regulator that contributes to the rapid transcriptional response of bacteria to many environmental changes.
Raphaël Forquet +4 more
doaj +1 more source
Contributions of supercoiling to Tn3 resolvase and phage Mu Gin site-specific recombination [PDF]
Members of the resolvase/invertase family of site-specific recombinases require supercoiled substrates containing two recombination sites. To dissect the roles of supercoiling in recombination by the Tn3 and γδ resolvases and the phage Mu Gin invertase ...
Abola, M.T.B. +3 more
core +2 more sources
Characterization of nuclear structures containing superhelical DNA
ABSTRACT Structures resembling nuclei but depleted of protein may be released by gently lysing cells in solutions containing non-ionic detergents and high concentrations of salt. These nucleoids sediment in gradients containing intercalating agents in a manner characteristic of DNA that is intact, supercoiled and circular.
Cook, P, Brazell, I, Jost, E
openaire +3 more sources
Spontaneous formation of liquid crystalline phases and phase transitions in highly concentrated plasmid DNA [PDF]
The liquid crystalline (LC) properties of two supercoiled plasmid DNA samples, pBSK (2958 bp) and pGEM (3000 bp), have been studied using polarised light microscopy (PLM), circular dichroism (CD) and UV-Vis spectroscopy.
Buckle, M. +5 more
core +2 more sources
Pentatricopeptide repeat proteins coordinate nucleus‐organelle communication by modulating RNA metabolism within chloroplasts and mitochondria. This review highlights how they control critical processes like photosynthesis, seed development, fertility restoration, and stress survival in crops, and explores their potential as programmable tools for RNA ...
Mingming Wu +7 more
wiley +1 more source
Mechanical response of plectonemic DNA: an analytical solution
We consider an elastic rod model for twisted DNA in the plectonemic regime. The molecule is treated as an impenetrable tube with an effective, adjustable radius.
Allemand J. F. +31 more
core +2 more sources

