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Glycolytic enzymes as DNA binding proteins
International Journal of Biochemistry, 19931. Numerous studies have demonstrated the presence of at least four glycolytic enzymes in the nuclear compartment of several cell systems. 2. These include, lactate dehydrogenase, phosphoglycerate kinase, aldolase and glyceraldehyde-3-phosphate dehydrogenase. 3.
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ASSAY and Drug Development Technologies, 2006
Quantitation of the level or activity of specific proteins is one of the most commonly performed experiments in biomedical research. Protein detection has historically been difficult to adapt to high throughput platforms because of heavy reliance upon antibodies for protein detection.
Benjamin, Dummitt, Yie-Hwa, Chang
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Quantitation of the level or activity of specific proteins is one of the most commonly performed experiments in biomedical research. Protein detection has historically been difficult to adapt to high throughput platforms because of heavy reliance upon antibodies for protein detection.
Benjamin, Dummitt, Yie-Hwa, Chang
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The Journal of Steroid Biochemistry and Molecular Biology, 1993
The glucocorticoid and thyroid hormone receptors have the capacity to bind as dimers to palindromic DNA-binding sites. Protein-protein interactions between the DNA-binding domains of glucocorticoid receptor dimers restrict the DNA-binding to elements where the half-sites are separated by three base pairs, whereas DNA-binding by the thyroid hormone ...
K, Dahlman-Wright +4 more
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The glucocorticoid and thyroid hormone receptors have the capacity to bind as dimers to palindromic DNA-binding sites. Protein-protein interactions between the DNA-binding domains of glucocorticoid receptor dimers restrict the DNA-binding to elements where the half-sites are separated by three base pairs, whereas DNA-binding by the thyroid hormone ...
K, Dahlman-Wright +4 more
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Crystallization of DNA binding proteins with oligodeoxynucleotides
Methods, 1990In contrast to oligodeoxynucleotides, protein:DNA complexes crystallize from a broad range of precipitants and conditions, much as proteins by themselves. There are, however, a number of factors that should be considered, at least in the early stages of cocrystallization attempts.
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HMG1 and 2: “architectural” DNA-binding proteins
Biochemical Society Transactions, 2001HMG1 and 2 (high mobility group proteins 1 and 2; renamed HMGB1 and 2) contain two DNA-binding HMG-box domains (A and B) and a long acidic C-terminal domain. They bind DNA without sequence specificity, but have a high affinity for bent or distorted DNA, and bend linear DNA.
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AlphaFold2-aware protein–DNA binding site prediction using graph transformer
Briefings in Bioinformatics, 2022Qianmu Yuan +2 more
exaly
DNAgenie: accurate prediction of DNA-type-specific binding residues in protein sequences
Briefings in Bioinformatics, 2021Sina Ghadermarzi +2 more
exaly