Results 11 to 20 of about 665,876 (395)

DNA polymerase of reticuloendotheliosis virus: Inability to detect endogenous RNA-directed DNA synthesis [PDF]

open access: green, 1975
Purified preparations of reticuloendotheliosis virus (REV) appear to lack the endogenous RNase-sensitive DNA polymerase activity present in most, if not all, avian RNA tumor viruses. Although no endogenous RNA-directed DNA polymerase could be detected in
Rita M. Kieras, Anthony J. Faras
openalex   +2 more sources

DNA-directed termination of mammalian RNA polymerase II

open access: goldGenes & Development
ABSTRACTThe best-studied mechanism of eukaryotic RNA polymerase II (RNAPII) transcriptional termination involves polyadenylation site-directed cleavage of the nascent RNA. The RNAPII-associated cleavage product is then degraded by XRN2, dislodging RNAPII from the DNA template.
Lee Davidson   +6 more
openalex   +3 more sources

Semi-rational evolution of a recombinant DNA polymerase for modified nucleotide incorporation efficiency. [PDF]

open access: yesPLoS ONE
Engineering improved B-family DNA polymerases to catalyze 3'-O-modified nucleotide reversible terminators is limited by an insufficient understanding of the structural determinants that define polymerization efficiency.
Lili Zhai   +10 more
doaj   +2 more sources

DNA-directed termination of RNA polymerase II transcription [PDF]

open access: yesMolecular Cell, 2023
RNA polymerase II (RNAPII) transcription involves initiation from a promoter, transcriptional elongation through the gene, and termination in the terminator region. In bacteria, terminators often contain specific DNA elements provoking polymerase dissociation, but RNAPII transcription termination is thought to be driven entirely by protein co-factors ...
Zhong Han   +7 more
openaire   +3 more sources

Human p53 interacts with the elongating RNAPII complex and is required for the release of actinomycin D induced transcription blockage [PDF]

open access: yes, 2017
The p53 tumour suppressor regulates the transcription initiation of selected genes by binding to specific DNA sequences at their promoters. Here we report a novel role of p53 in transcription elongation in human cells.
Boros, I.M. (Imre M.)   +7 more
core   +11 more sources

Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1

open access: greenNature, 2013
Julie A. Law   +8 more
openalex   +3 more sources

Acceleration of DNA Replication of Klenow Fragment by Small Resisting Force [PDF]

open access: yesChin. Phys. Lett. 2021, 38 (11): 118701, 2021
DNA polymerases are an essential class of enzymes or molecular motors that catalyze processive DNA syntheses during DNA replications. A critical issue for DNA polymerases is their molecular mechanism of processive DNA replication. We have previously proposed a model for chemomechanical coupling of DNA polymerases, based on which the predicted results ...
arxiv   +1 more source

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