Results 11 to 20 of about 97,697 (191)

In silico Evaluation of the Potential of Natural Products from Chili Pepper as Antiviral Agents Against Dna-Directed Rna Polymerase of the Monkeypox Virus

open access: goldBitlis Eren Üniversitesi Fen Bilimleri Dergisi
This study focused on the discovery of new drug candidates effective against the monkeypox virus. Virtual screening was performed to evaluate the potential of chili pepper natural products against homology-modeled DNA-directed RNA polymerase of the monkeypox virus using molecular docking. Our findings revealed that structurally similar triterpenes such
Özkan Fidan, Somdutt Mujwar
openalex   +5 more sources

Directed evolution of novel polymerase activities: Mutation of a DNA polymerase into an efficient RNA polymerase [PDF]

open access: greenProceedings of the National Academy of Sciences of the United States of America, 2002
Gang Xia   +5 more
openalex   +2 more sources

Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1

open access: greenNature, 2013
Julie A. Law   +8 more
openalex   +3 more sources

DNA-directed termination of RNA polymerase II transcription [PDF]

open access: yesMolecular Cell, 2023
RNA polymerase II (RNAPII) transcription involves initiation from a promoter, transcriptional elongation through the gene, and termination in the terminator region. In bacteria, terminators often contain specific DNA elements provoking polymerase dissociation, but RNAPII transcription termination is thought to be driven entirely by protein co-factors ...
Zhong Han   +7 more
openaire   +3 more sources

Structural dynamic investigation of the mutation-induced resistance mechanisms of Mycobacterium tuberculosis DNA-directed RNA polymerase against Rifampicin

open access: hybrid
Emerging resistant strains of Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB) disease, continue to plague mankind and reduce the efficacies of antitubercular therapies that have been an effective defence against TB for decades.
Mokgerwa Zacharia Monama
openalex   +3 more sources

Relationship Between RNA-directed DNA Polymerase (Reverse Transcriptase) from Human Acute Leukemic Blood Cells and Primate Type-C Viruses [PDF]

open access: greenProceedings of the National Academy of Sciences of the United States of America, 1974
Robert E. Gallagher   +4 more
openalex   +2 more sources

DNA topoisomerase 1α promotes transcriptional silencing of transposable elements through DNA methylation and histone lysine 9 dimethylation in Arabidopsis. [PDF]

open access: yesPLoS Genetics, 2014
RNA-directed DNA methylation (RdDM) and histone H3 lysine 9 dimethylation (H3K9me2) are related transcriptional silencing mechanisms that target transposable elements (TEs) and repeats to maintain genome stability in plants. RdDM is mediated by small and
Thanh Theresa Dinh   +14 more
doaj   +1 more source

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