Results 11 to 20 of about 97,697 (191)
This study focused on the discovery of new drug candidates effective against the monkeypox virus. Virtual screening was performed to evaluate the potential of chili pepper natural products against homology-modeled DNA-directed RNA polymerase of the monkeypox virus using molecular docking. Our findings revealed that structurally similar triterpenes such
Özkan Fidan, Somdutt Mujwar
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Directed evolution of novel polymerase activities: Mutation of a DNA polymerase into an efficient RNA polymerase [PDF]
Gang Xia +5 more
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Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1
Julie A. Law +8 more
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DNA-directed termination of RNA polymerase II transcription [PDF]
RNA polymerase II (RNAPII) transcription involves initiation from a promoter, transcriptional elongation through the gene, and termination in the terminator region. In bacteria, terminators often contain specific DNA elements provoking polymerase dissociation, but RNAPII transcription termination is thought to be driven entirely by protein co-factors ...
Zhong Han +7 more
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Emerging resistant strains of Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB) disease, continue to plague mankind and reduce the efficacies of antitubercular therapies that have been an effective defence against TB for decades.
Mokgerwa Zacharia Monama
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Relationship Between RNA-directed DNA Polymerase (Reverse Transcriptase) from Human Acute Leukemic Blood Cells and Primate Type-C Viruses [PDF]
Robert E. Gallagher +4 more
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DNA topoisomerase 1α promotes transcriptional silencing of transposable elements through DNA methylation and histone lysine 9 dimethylation in Arabidopsis. [PDF]
RNA-directed DNA methylation (RdDM) and histone H3 lysine 9 dimethylation (H3K9me2) are related transcriptional silencing mechanisms that target transposable elements (TEs) and repeats to maintain genome stability in plants. RdDM is mediated by small and
Thanh Theresa Dinh +14 more
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