Results 201 to 210 of about 108,714 (328)

What is in a name? Rethinking SMUG1 in genome maintenance. [PDF]

open access: yesNAR Cancer
Rudolfova N   +5 more
europepmc   +1 more source

Coupling of both a transactivation module and a double‐stranded DNA‐binding domain boosts Cas12i3 variant‐based cytosine and adenine editing in plants

open access: yesJournal of Integrative Plant Biology, EarlyView.
Fusions of a transactivation module and a double‐stranded DNA‐binding domain produced effective Cas12i3 variant‐based cytosine and adenine base editors, with improved C‐to‐T and A‐to‐G base editing efficiency and expanded editing window. Generated herbicide‐resistant rice germplasm by using these base editors demonstrates their potential for precise ...
Chen Zhang   +7 more
wiley   +1 more source

Are i-Motif Structures in DNA Compatible with Cytosine-Ag(I)-Cytosine Base Pairs? [PDF]

open access: yesAngew Chem Int Ed Engl
Seiffert V   +8 more
europepmc   +1 more source

Optimizations of Cas12a‐ and Cas12i‐based adenine base editors for efficient precision editing in the plant genome

open access: yesJournal of Integrative Plant Biology, EarlyView.
A strategy coupling high‐activity nucleases with dimeric TadA‐8e optimizes plant Cas12‐based adenine base editors, boosts editing efficiency, and provides precise editors for crop breeding and genomics research.
Xiaoshuang Liu   +11 more
wiley   +1 more source

PolyA tail segmentation improves the stability of the template DNA and increases the translatability of in vitro transcribed mRNA. [PDF]

open access: yesNucleic Acids Res
Spiewla T   +15 more
europepmc   +1 more source

The Role of Oxidative Stress in Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon   +3 more
wiley   +1 more source

Development of a markerless tool for targeted chromosome modification in the thermophilic and methylotrophic bacterium Bacillus methanolicus. [PDF]

open access: yesMicrob Cell Fact
Irla M   +8 more
europepmc   +1 more source

Erythrocyte Membrane Protein 3 (EMAP3) Is Exposed on the Surface of the Plasmodium berghei Infected Red Blood Cell

open access: yesMolecular Microbiology, EarlyView.
Erythrocyte membrane protein 3 (EMAP3) is a novel Plasmodium berghei protein that is trafficked to the outer membrane surface of the infected red blood cell (iRBC). EMAP3 is not critical for parasite growth or sequestration but offers a new scaffold for displaying Plasmodium falciparum proteins on iRBCs.
Sophia Raine C. Hernandez   +13 more
wiley   +1 more source

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