Targeting dCas9-SunTag to a Susceptibility Gene Promoter Is Sufficient for CRISPR Interference. [PDF]
Lin ZD +14 more
europepmc +1 more source
Advances in MoS2‐Au Nanostructured Platforms for Cancer‐Derived miRNA Detection
This figure presents the roadmap and scope of this review on microRNA detection technologies, with emphasis on MoS2 and MoS2–Au hybrid nanostructures. It traces the evolution from conventional assays to MoS2‐based SERS platforms, highlights synthesis, interfacial chemistry, and signal‐enhancement mechanisms, and summarizes key challenges and future ...
Faith Mokobi Zablon +2 more
wiley +1 more source
<i>Cubilin</i> gene mutation screening in Thai Border Collies using double-mismatch allele-specific and multiplex polymerase chain reaction: Implications for Imerslund-Gräsbeck syndrome. [PDF]
Lerdkrai C +2 more
europepmc +1 more source
Rapid transcriptome responses of maize () to UV-B in irradiated and shielded tissues [PDF]
core +1 more source
A miniaturized deaminase SsdAtox was scanned with AlphaFold to identify DNA binding pocket hot spots. Site‐saturation mutagenesis at gatekeeper residue K31 yielded ten‐fold activity enhancement. Trinity Screen, an E. coli‐based three‐in‐one platform selecting for high activity and reduced double‐strand breaks, enabled combinatorial evolution at DNA ...
Ryeo Gang Son +2 more
wiley +1 more source
Deaminase-Assisted Sequencing for the Identification of 5-glyceryl-methylcytosine. [PDF]
He BD, Wang FC, Xue JH.
europepmc +1 more source
Repeated disuse imprints a molecular memory in skeletal muscle, conferring transcriptional resilience in young adults but exaggerated susceptibility in aged muscle, driven by epigenetic regulation of aerobic metabolism, mitochondrial and NAD+ pathways.
Daniel C. Turner +14 more
wiley +1 more source
High cancer-associated mutational burden in normal blood of xeroderma pigmentosum group C, but not groups A, D, or F. [PDF]
Fan-Huang G +8 more
europepmc +1 more source
Genomic Variants Associated With Oocyte and Embryo Production in Dairy Gir Cattle
ABSTRACT The use of in vitro fertilization protocols associated with genomic selection increases genetic gain in dairy cattle. The aims of this study were to uncover genetic variants in a specific interval on BTA7 and to investigate their effects on the number of oocytes and embryos in dairy Gir.
Renata de Fatima Bretanha Rocha +6 more
wiley +1 more source
Nanopore-Based, Real-Time Single-Molecule Probing of i-Motif Structural Dynamics and Targeted PNA Disruption. [PDF]
Cimpanu A +4 more
europepmc +1 more source

