Results 211 to 220 of about 95,440 (308)

Targeting dCas9-SunTag to a Susceptibility Gene Promoter Is Sufficient for CRISPR Interference. [PDF]

open access: yesPlant Direct
Lin ZD   +14 more
europepmc   +1 more source

Advances in MoS2‐Au Nanostructured Platforms for Cancer‐Derived miRNA Detection

open access: yesAdvanced Materials Interfaces, Volume 13, Issue 8, 21 April 2026.
This figure presents the roadmap and scope of this review on microRNA detection technologies, with emphasis on MoS2 and MoS2–Au hybrid nanostructures. It traces the evolution from conventional assays to MoS2‐based SERS platforms, highlights synthesis, interfacial chemistry, and signal‐enhancement mechanisms, and summarizes key challenges and future ...
Faith Mokobi Zablon   +2 more
wiley   +1 more source

Engineering Compact Base Editors by AlphaFold‐Guided Mutation Scan and Escherichia coli‐Based Tri‐Selection

open access: yesAdvanced Science, Volume 13, Issue 20, 9 April 2026.
A miniaturized deaminase SsdAtox was scanned with AlphaFold to identify DNA binding pocket hot spots. Site‐saturation mutagenesis at gatekeeper residue K31 yielded ten‐fold activity enhancement. Trinity Screen, an E. coli‐based three‐in‐one platform selecting for high activity and reduced double‐strand breaks, enabled combinatorial evolution at DNA ...
Ryeo Gang Son   +2 more
wiley   +1 more source

Repeated Disuse Atrophy Imprints a Molecular Memory in Skeletal Muscle: Transcriptional Resilience in Young Adults and Susceptibility in Aged Muscle

open access: yesAdvanced Science, Volume 13, Issue 23, 23 April 2026.
Repeated disuse imprints a molecular memory in skeletal muscle, conferring transcriptional resilience in young adults but exaggerated susceptibility in aged muscle, driven by epigenetic regulation of aerobic metabolism, mitochondrial and NAD+ pathways.
Daniel C. Turner   +14 more
wiley   +1 more source

High cancer-associated mutational burden in normal blood of xeroderma pigmentosum group C, but not groups A, D, or F. [PDF]

open access: yesBlood Neoplasia
Fan-Huang G   +8 more
europepmc   +1 more source

Genomic Variants Associated With Oocyte and Embryo Production in Dairy Gir Cattle

open access: yesAnimal Genetics, Volume 57, Issue 2, April 2026.
ABSTRACT The use of in vitro fertilization protocols associated with genomic selection increases genetic gain in dairy cattle. The aims of this study were to uncover genetic variants in a specific interval on BTA7 and to investigate their effects on the number of oocytes and embryos in dairy Gir.
Renata de Fatima Bretanha Rocha   +6 more
wiley   +1 more source

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