Redox‐active guanidines, comprising guanidino‐functionalized aromatics (GFAs) and redox‐active urea azines (RAAs), are electron donors and strong Lewis and Brønsted bases that are used in several applications. They act as redox‐active ligands in bistable coordination compounds and as reagents in dehydrogenative coupling reactions and proton‐coupled ...
Hans‐Jörg Himmel
wiley +1 more source
Analysis of Cytosine Base Editors in Bovine Zygotes: Efficiency and Editing Window Characterization Through Targeting the <i>MYO7A</i> Gene. [PDF]
Ryu J +3 more
europepmc +1 more source
Using kanamycin A as a model target, we developed click‐capture SELEX to identify nucleobase‐modified aptamers capable of binding small molecules in solution. This approach enables flexible incorporation of nucleobase modifications via CuAAC, allowing the chemical properties of the aptamer to be tailored to the target molecule.
Philipp Menke +5 more
wiley +1 more source
Heavy Water Remodels the DNA Energy Landscape to Stabilize Folded States and Slow Transitions. [PDF]
Kim SE +5 more
europepmc +1 more source
Advances in CRISPR Base Editing: From Molecular Evolution to Therapeutic Applications in Genomic Medicine. [PDF]
Aliciaslan M +3 more
europepmc +1 more source
The Hoechst Dye‐Binding RNA Aptamer Recognizes Its Ligand in a Highly Dynamic Fashion
The Hoechst–RNA aptamer binds a tert‐butyl containing derivative of the Hoechst dye. The study presented here shows that the interactions between the RNA and ligand are highly dynamic with the ligand occupying two overlapping binding sites. The interactions are explored using NMR spectroscopy and time‐resolved fluorescence.
Natasha M. Evans +2 more
wiley +1 more source
MDNA : a software module for DNA structure generation and analysis. [PDF]
van Heesch T +4 more
europepmc +1 more source
Draft genome sequence of a resistant diesel fuel degrader <i>Rhodococcus ruber</i> IEGM 442. [PDF]
Komarova L +3 more
europepmc +1 more source
Research note: Comparative identification of higher-order quadruplex structures in the LEP locus of galliformes. [PDF]
Ahn J, Lee K.
europepmc +1 more source
Expanding the genetic toolkit: adenine and cytosine base editors for gene disruption in Aspergillus niger. [PDF]
Yuan G +4 more
europepmc +1 more source

