Results 171 to 180 of about 671,892 (268)

Histone PARylation factor 1: a review of its role in the DNA damage response. [PDF]

Nucleic Acids Res
Rudolph J, Luger K.
europepmc   +1 more source

The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen, Ali Behram Salar, Abdulkadir Ermis, Erkingul Birday, Lutfu Hanoglu, Bayram Ufuk Sakul   +5 more
wiley   +1 more source

DNA Damage Response and Redox Status in the Resistance of Multiple Myeloma Cells to Genotoxic Treatment. [PDF]

Int J Mol Sci
Malamos P, Papanikolaou C, Deligianni E, Mavroeidi D, Koutoulogenis K, Gavriatopoulou M, Terpos E, Souliotis VL.   +7 more
europepmc   +1 more source

Multi‐Omics Integration for Advancing Glioma Precision Medicine

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas are among the most malignant and aggressive tumors of the central nervous system, characterized by the absence of early diagnostic markers, poor prognosis, and a lack of effective treatments. Advances in high‐throughput technologies have facilitated a refined molecular classification of gliomas, incorporating genetic features. However,
Maria Guarnaccia, Valentina La Cognata, Giulia Gentile, Giovanna Morello, Sebastiano Cavallaro   +4 more
wiley   +1 more source

The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4

, 2015
Chanhee Kang, Qikai Xu, Timothy D. Martin, Mamie Z. Li, Marco Demaria, Liviu Aron, Tao Lu, Bruce A. Yankner, Judith Campisi, Stephen J. Elledge   +9 more
openalex   +1 more source

MINA53 deficiency leads to glioblastoma cell apoptosis via inducing DNA replication stress and diminishing DNA damage response [PDF]

, 2018
Xuan Fan, Mengying Huang, Erhu Zhao, Hongjuan Cui   +3 more
openalex   +1 more source

Methionine deficiency causes spermatogonial apoptosis via oxidative stress and DNA damage response pathway. [PDF]

Biol Res
Wang W, Ruan Y, Ting G.
europepmc   +1 more source

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang   +9 more
wiley   +1 more source

Thymine DNA glycosylase modulates DNA damage response and gene expression by base excision repair‐dependent and independent mechanisms [PDF]

, 2017
Tomohumi Nakamura, Kouichi Murakami, Haruto Tada, Yoshihiko Uehara, Jumpei Nogami, Kazumitsu Maehara, Yasuyuki Ohkawa, Hisato Saitoh, Hideo Nishitani, Tetsuya Ono, Ryotaro Nishi, Masayuki Yokoi, Wataru Sakai, Kaoru Sugasawa   +13 more
openalex   +1 more source

Anti-Müllerian Hormone Ameliorates Uterine DNA Damage Response and Prevents Pregnancy Complications in Doxorubicin-Treated Mice†. [PDF]

Biol Reprod
Nguyen NMP, Mermin-Bunnell AM, Mattos K, Cleverdon J, Kano M, Chauvin M, Godin P, Kashiwagi A, Duong T, Nagykery N, Donahoe PK, Meinsohn MC, Pepin D.   +12 more
europepmc   +1 more source