Results 201 to 210 of about 96,036 (271)

TET1-mediated DNA demethylation suppresses migration of goat placental trophoblast cells. [PDF]

J Anim Sci
Sun Z, Tang Y, Liao Y, Ma X, Wang M, Fang X, Yang S, Zhao J, Zhao Y.   +8 more
europepmc   +1 more source

The multifaceted roles of the ACSL family in cancer: Metabolic reprogramming, ferroptosis regulation and tumour immune microenvironment remodelling

Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.
The acyl‐CoA synthetase long‐chain (ACSL) family consists of five members, which exhibit a synergistic effect in promoting tumour lipid metabolism for energy supply. Specifically, ACSL3 and ACSL4 have antagonistic effects on the mechanisms related to ferroptosis in tumour cells.
Haocai Li, Weijian Wang, Juncheng Zhan, Yuxiang Xiao, Xiaoping Chen, Chen Su, Peng Zhu   +6 more
wiley   +1 more source

Dimethyl sulfoxide-induced DNA demethylation during vitrification of early cleavage-stage embryos and possible countermeasures. [PDF]

J Assist Reprod Genet
Shida M, Ito J, Inoue Y, Hara S, Shirasuna K, Iwata H.   +5 more
europepmc   +1 more source

ME-Class2 reveals context dependent regulatory roles for 5-hydroxymethylcytosine [PDF]

, 2019
Edwards, John R, Gabel, Harrison W, Schlosberg, Christopher E, Wu, Dennis Y   +3 more
core   +1 more source

Volatile Organic Compound Release During Litter Decomposition in the Arctic

Global Change Biology Communications, Volume 1, Issue 1, March 2026.
Volatile organic compound (VOC) emissions from Arctic litter decomposition decline over time and differ strongly between Cassiope tetragona and Salix arctica. The inter‐species differences and changes over time are greater than the effects of climate change treatments on litter VOC emissions.
Riikka Rinnan, Mira Skardhamar, Magnus Kramshøj, Tao Li, Sarah H. Svendsen, Toke Bang‐Andreasen, Lars H. Hansen, Thomas Holst   +7 more
wiley   +1 more source

Transposition element MERVL regulates DNA demethylation through TET3 in oxidative-damaged mouse preimplantation embryos. [PDF]

Mol Med
Liu L, Ha S, Cao D, Li M, Li Z.
europepmc   +1 more source

ALKBH5‐Driven m6A Demethylation Boosts Inflammation and Autophagy in LPS‐Stimulated Macrophages

Immunity, Inflammation and Disease, Volume 14, Issue 3, March 2026.
ABSTRACT Purpose Acute Respiratory Distress Syndrome (ARDS) remains a critical health threat with limited pharmacological treatments. This study investigates the role of the N6‐methyladenosine (m6A) demethylase AlkB homolog 5 (ALKBH5) in alveolar macrophages and its subsequent impact on inflammation and autophagy during ARDS pathogenesis.
Gui Wang, Ting Zhou, Shujun Zhou
wiley   +1 more source

Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation. [PDF]

Nat Commun
Tan J, Li Y, Li X, Zhu X, Liu L, Huang H, Wei J, Wang H, Tian Y, Wang Z, Zhang Z, Zhu B.   +11 more
europepmc   +1 more source

RNA Regulatory Networks: Key Hubs in the Panorama of Cancer and Emerging Therapeutic Targets

MedComm, Volume 7, Issue 3, March 2026.
RNA regulatory networks play a crucial role in the initiation and progression of cancer through various modes of RNA interactions. Notably, circulating RNAs have emerged as potential biomarkers, while targeted interventions in RNA regulatory networks facilitate precise therapeutic strategies. ABSTRACT Cancer is a global health challenge. The initiation
Xuan Yin, Zengkan Du, Shuya Jiang, Yan Liao, Changli Wang, Jiaqi Li, Haoling Zhang, Ting‐Ting Wei, Wangzheqi Zhang, Zui Zou   +9 more
wiley   +1 more source

Chromatin Accessibility in Cancer: Biological Functions, Mechanisms, Therapeutic Potential, and Future Directions

MedComm, Volume 7, Issue 3, March 2026.
Cancer remains the leading cause of mortality worldwide, and drug resistance further underscores the urgent need for innovative therapeutic strategies. Chromatin, a stable yet highly dynamic nucleoprotein complex, serves as the primary carrier of genetic material in eukaryotic cells.
Wentao Xia, Min Jiang, Yefei Huang, Kun Ding, Yansu Chen   +4 more
wiley   +1 more source