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Global Andrology Forum Clinical Guidelines on the Relevance of Sperm DNA Fragmentation in Reproductive Medicine. [PDF]

World J Mens Health
Çayan S, Farkouh A, Agarwal A, Atmoko W, Wyns C, Arafa M, Zini A, Shah R, Alipour H, Chung E, Saleh R, Pinggera GM, Konstantinidis C, Al Hashimi M, Pescatori E, Rambhatla A, Toprak T, Calogero AE, Gül M, Park HJ, Altay B, Falcone M, Rashed A, Le TV, Bahar F, Shatylko T, Görür S, El-Sakka AI, Saylam B, Sarikaya S, Smith RP, Boeri L, Efesoy O, Ceyhan E, Russo GI, Ozer C, Ho CCK, Gungor ND, Özlü DN, Molina JMC, Musa MU, Tsujimura A, Gokalp F, Mohamed MS, Okada K, Khalafalla K, Kuroda S, Binsaleh S, Motawi AT, Shamohammadi I, Mogharabian N, Manh MT, Taha EA, Makarounis K, Mak SK, Shedeed SA, Thomas C, Mostafa T.   +57 more
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Impact of sperm DNA fragmentation index on assisted reproductive outcomes: a retrospective analysis. [PDF]

Front Endocrinol (Lausanne)
Yang B, Xia L, Deng R, Wu L, Zhang Z, Wu X, Ding T, Zhao Y, Huang J, Huang Z.   +9 more
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Correction to "Age, sexual abstinence duration, sperm morphology, and motility are predictors of sperm DNA fragmentation". [PDF]

Reprod Med Biol
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Sperm DNA Fragmentation

Seminars in Reproductive Medicine, 2021
AbstractSperm DNA fragmentation refers to the accumulation of adducts as well as single- or double-strand DNA breaks and reflects the sperm DNA quality. Current data suggest that there are differences in sperm DNA quality among individuals with high or low fertility, and this observation has led to the idea that testing sperm DNA fragmentation could be
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Apoptotic DNA Fragmentation

Experimental Cell Research, 2000
Degradation of nuclear DNA into nucleosomal units is one of the hallmarks of apoptotic cell death. It occurs in response to various apoptotic stimuli in a wide variety of cell types. Molecular characterization of this process identified a specific DNase (CAD, caspase-activated DNase) that cleaves chromosomal DNA in a caspase-dependent manner.
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Extracellular DNA Fragments

Annals of the New York Academy of Sciences, 2008
During the development of the adaptive response, the pericentromeric loci of homologous chromosomes appear to move from the perimembrane sites of the cell nucleus and approach each other for a possible repair of double‐stranded breaks of DNA in the process of homologous recombination.
Aleksei V. Ermakov, Svetlana V. Kostyuk, Marina S. Konkova, Natalya A. Egolina, Elena M. Malinovskaya, Natalya N. Veiko   +5 more
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Quantitative Evaluation of DNA Fragmentation

Bulletin of Experimental Biology and Medicine, 2002
A new method for evaluation of DNA fragmentation in tissue is based on computer-aided densitometric standardization of the sum of optical densities of DNA fragments visualized by electrophoresis (180-2500 b. p.) in comparison with the density of high molecular weight DNA in the same sample.
T S, Kalinina, A V, Bannova, N N, Dygalo
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Necrosis has orderly DNA fragmentations

Biochemical and Biophysical Research Communications, 2002
Necrosis from freezing manifested an orderly pattern of DNA fragmentations, including the apoptosis signature of 200 bp ladder, in three different cell populations, despite pancaspase suppression by zVAD-fmk. Immediately on thawing, all three populations had 100% dead cell indices and 2.2, 1.6, and 1.1 megabase fragmentations, which marked the point of
Kok, Y.-J., Swe, M., Sit, K.-H.
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A hypervariable pig DNA fragment

Animal Genetics, 1990
Summary A new hypervariable tandem repeat was isolated from the pig genome and characterized by DNA sequence. The use of this DNA fragment as a probe in order to follow allelic segregation and DNA fingerprinting in pigs, horses and rabbits is documented.
W, Coppieters, A, Van de Weghe, A, Depicker, Y, Bouquet, A, Van Zeveren   +4 more
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Nucleosomal DNA Fragments in Autoimmune Diseases

Annals of the New York Academy of Sciences, 2006
Abstract:  The inadequate response of immune cells to circulating apoptotic products, such as nucleosomal DNA fragments, is assumed to be a potent stimulus for the production of autoantibodies during the pathogenesis and progression of systemic lupus erythematosus (SLE). Here, we analyzed the levels of circulating nucleosomes, caspases, and C‐reactive
Holdenrieder, Stefan, Eichhorn, Peter, Beuers, Ulrich, Samtleben, Walter, Schoenermarck, Ulf, Zachoval, Reinhart, Nagel, Dorothea, Stieber, Petra   +7 more
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