Results 231 to 240 of about 1,932,999 (290)

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

Evaluating the potential for sperm DNA fragmentation testing to guide the use of ICSI for couples with non-severe male infertility. [PDF]

Hum Reprod Open
Wang Y, Wang R, Lian Y, Yang R, Gao J, Liu J, Tang L, Liang X, Cao Y, Li W, Jin L, Zhu Y, Zhao J, Hao G, Wang H, Mol BW, Li R, Qiao J.   +17 more
europepmc   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

Evaluation of Oxidative Stress and Its Impact on Sperm DNA Fragmentation and Semen Parameters in Infertile Men. [PDF]

ScientificWorldJournal
Berrada K, Touhamia Y, Serbouti A, Aamiri A, Ousaid FE, Housbane S, Kabine M, Louanjli N, Aboutaieb R.   +8 more
europepmc   +1 more source

UDP‐Glucose‐6‐Dehydrogenase Mediated O‐GlcNAcylation of Tight Junction Protein 1 Suppresses Metastasis in Renal Cell Carcinoma

Advanced Science, EarlyView.
Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen, Yuhang Bao, Tao Liu, Jianhui Qiu, Yuanyuan Ma, Zedan Zhang, Chuandong Wang, Ruiyi Deng, Zheng Song, Tianyi He, Haode Liu, Jingcheng Zhou, Yizhou Wang, Kan Gong   +13 more
wiley   +1 more source

Flow Cytometric Assessment of Sperm DNA Fragmentation by TUNEL and Acridine Orange: Methodological and Clinical Insights. [PDF]

J Clin Med
Abdelkarim M, Ghannem N, Kacem-Berjeb K, Chtourou S, Debbabi L, Fadhlaoui A, Ben Mefeteh M, Zhioua F, Braham M, Chakroun N.   +9 more
europepmc   +1 more source

Comparison of Different Sperm Isolation Strategies for Fresh and Cryopreserved Human Spermatozoa Using a Simple Method for Simultaneously Assessing Sperm Vitality and DNA Fragmentation. [PDF]

Andrology
Aitken RJ, Lambourne S, Sheridan A, Bakos HW.   +3 more
europepmc   +1 more source

In Vitro Effects of Mentha suaveolens, Rosmarinus officinalis, and Lippia citriodora Essential Oils on Sperm Motility, Vitality, and DNA Fragmentation. [PDF]

Cureus
Hilali C, Benkhalifa M, Nadifi C, Kettani Halabi M, Bouanani N, Louanjli N, Lahlou FA.   +6 more
europepmc   +1 more source

Comparative Analysis of Cell-Free DNA Fragmentation Patterns in Canines with Sarcoma and Tumor-Free Canines and Humans. [PDF]

Cancer Res Commun
Favaro PF, Wang Y, McDonald BR, Wang TX, Jadhav S, Cheng HH, Marcinak CT, Pan X, Murtaza M.   +8 more
europepmc   +1 more source

Association Among Sperm Adiponectin, DNA Fragmentation, Oxidative Stress and Metabolites in Male Infertility. [PDF]

Antioxidants (Basel)
Militello R, Traini G, Pinto G, Gamberi T, Luti S, Marchiani S, Illiano A, Vignozzi L, Amoresano A, Modesti A.   +9 more
europepmc   +1 more source