Results 241 to 250 of about 222,504 (300)

Effect of sperm DNA fragmentation on embryo euploidy rate in assisted reproductive technologies: a systematic review and meta-analysis. [PDF]

Eur J Med Res
Wan B, Fu Y, Ma N, Zhou Z, Lu W.
europepmc   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source

Viable sperm DNA fragmentation index (SDF) provides better diagnostic accuracy than total SDF in male infertility: a cross-sectional study. [PDF]

Transl Androl Urol
Deng T, Yu W, Yao J, Li X, Fu Z, Xie Y, Pu J, Chen K, Yao B, Lin X, Wang W.   +10 more
europepmc   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

Author Correction: RNaseH2A downregulation drives inflammatory gene expression via genomic DNA fragmentation in senescent and cancer cells. [PDF]

Commun Biol
Sugawara S, Okada R, Loo TM, Tanaka H, Miyata K, Chiba M, Kawasaki H, Katoh K, Kaji S, Maezawa Y, Yokote K, Nakayama M, Oshima M, Nagao K, Obuse C, Nagayama S, Takubo K, Nakanishi A, Kanemaki MT, Hara E, Takahashi A.   +20 more
europepmc   +1 more source

Sperm DNA Fragmentation in Men with Varicocele: A Systematic Review and Meta-Analysis. [PDF]

World J Mens Health
Palani A, Çayan S, Cannarella R, Saleh R, Altay B, Kadihasanoglu M, Harraz A, Dimitriadis F, Ceyhan E, Rezano A, Zwamel AH, Ibrahim W, Benabbou A, Margiana R, Gnoneye E, Rabin MMM, Omirinde J, Esmaeili V, Zini A, Arafa M, Elbardisi H, Toprak T, Dursun M, Khalafalla K, Salvio G, Chung E, Crafa A, Shah R, Agarwal A.   +28 more
europepmc   +1 more source

Impact of ejaculation frequency on semen parameters and DNA fragmentation: a cross-sectional study. [PDF]

Reprod Biol Endocrinol
Xi Q, Kong Q, Lv X, Dai R, Yu Y.
europepmc   +1 more source

The Relationship Between Sperm Midpiece Details and DNA Fragmentation in Human Sperm. [PDF]

Reprod Sci
Ibis MA, Mencik NO, Öztürk B, Karaburun MC, Akpinar C, Akıncı A, Haberal HB, Aydos K, Yaman O.   +8 more
europepmc   +1 more source

DNA FRAGMENTATION IN APOPTOSIS

TISSUE CULTURE RESEARCH COMMUNICATIONS, 1995
openaire   +1 more source

Fine particulate matter exposure and sperm DNA fragmentation in US men: a spatial cross-sectional study. [PDF]

Hum Reprod
Fouks Y, Vaughan DA, Bortoletto P, Chang JC, Lantsberg D, Datta VX, McSweeney B, Schwartz JD, Sakkas D.   +8 more
europepmc   +1 more source