Results 131 to 140 of about 2,011,431 (260)

A ratiometric electrochemical assay for human 8-oxoguanine DNA glycosylase amplified by hybridization chain reaction

open access: yesElectrochemistry Communications, 2019
Human 8-oxoguanine DNA glycosylase 1 (hOGG1) is an important DNA repair enzyme, which is closely related to the occurrence and development of certain diseases.
Dawei Yang   +3 more
doaj  

Uracil-DNA glycosylase of thermophilic Thermothrix thiopara [PDF]

open access: bronze, 1985
O. K. Kaboev   +2 more
openalex   +1 more source

Harnessing novel cytidine deaminases from the animal kingdom for robust multiplexed base editing in rice

open access: yesPlant Biotechnology Journal, Volume 23, Issue 5, Page 1702-1712, May 2025.
Summary CRISPR‐Cas‐based cytosine base editors (CBEs) are prominent tools that perform site‐specific and precise C‐to‐T conversions catalysed by cytidine deaminases. However, their use is often constrained by stringent editing preferences for genomic contexts, off‐target effects and restricted editing windows.
Danyel Fernandes Contiliani   +7 more
wiley   +1 more source

PERFUME: detection of 8-oxoguanine DNA glycosylase activity based on primer exchange reaction and functionalized hemin/G-quadruplex DNAzyme

open access: yesTalanta Open
Background: 8-oxoguanine DNA glycosylase can maintain genomic stability and integrity. However, it can interfere with the regular DNA damage repair process, possibly leading to the development of cancer and various other human diseases when its activity ...
Kaiting Xiao   +8 more
doaj  

The ‘very moment’ when UDG recognizes a flipped-out uracil base in dsDNA

open access: yesScientific Reports
Uracil-DNA glycosylase (UDG) is the first enzyme in the base-excision repair (BER) pathway, acting on uracil bases in DNA. How UDG finds its targets has not been conclusively resolved yet.
Vinnarasi Saravanan   +6 more
doaj   +1 more source

Molecular Dynamics Simulations of a Nucleosome and Free DNA [PDF]

open access: yesarXiv, 2004
Nucleosomes organize the folding of DNA into chromatin and significantly influence transcription, replication, regulation and repair. All atom molecular dynamics simulations of a nucleosome and of its 146 basepairs of DNA free in solution have been conducted.
arxiv  

A stage‐dependent seed defense response to explain efficient seed transmission of Xanthomonas citri pv. fuscans to common bean

open access: yesPlant, Cell &Environment, EarlyView.
Abstract Although seed represents an important means of plant pathogen dispersion, the seed–pathogen dialogue remains largely unexplored. A multiomic approach was performed at different seed developmental stages of common bean (Phaseolus vulgaris L.) during asymptomatic colonization by Xanthomonas citri pv.
Armelle Darrasse   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy