Results 131 to 140 of about 2,011,431 (260)
Demonstration of pyrimidine dimer-DNA glycosylase activity in vivo: bacteriophage T4-infected Escherichia coli as a model system [PDF]
Eric H. Radany, E C Friedberg
openalex +1 more source
Human 8-oxoguanine DNA glycosylase 1 (hOGG1) is an important DNA repair enzyme, which is closely related to the occurrence and development of certain diseases.
Dawei Yang+3 more
doaj
Uracil-DNA glycosylase of thermophilic Thermothrix thiopara [PDF]
O. K. Kaboev+2 more
openalex +1 more source
Summary CRISPR‐Cas‐based cytosine base editors (CBEs) are prominent tools that perform site‐specific and precise C‐to‐T conversions catalysed by cytidine deaminases. However, their use is often constrained by stringent editing preferences for genomic contexts, off‐target effects and restricted editing windows.
Danyel Fernandes Contiliani+7 more
wiley +1 more source
Background: 8-oxoguanine DNA glycosylase can maintain genomic stability and integrity. However, it can interfere with the regular DNA damage repair process, possibly leading to the development of cancer and various other human diseases when its activity ...
Kaiting Xiao+8 more
doaj
The ‘very moment’ when UDG recognizes a flipped-out uracil base in dsDNA
Uracil-DNA glycosylase (UDG) is the first enzyme in the base-excision repair (BER) pathway, acting on uracil bases in DNA. How UDG finds its targets has not been conclusively resolved yet.
Vinnarasi Saravanan+6 more
doaj +1 more source
Molecular Dynamics Simulations of a Nucleosome and Free DNA [PDF]
Nucleosomes organize the folding of DNA into chromatin and significantly influence transcription, replication, regulation and repair. All atom molecular dynamics simulations of a nucleosome and of its 146 basepairs of DNA free in solution have been conducted.
arxiv
Selective RNA amplification: a novel method using dUMP-containing primers and uracil DNA glycosylase. [PDF]
George W. Buchman+2 more
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Abstract Although seed represents an important means of plant pathogen dispersion, the seed–pathogen dialogue remains largely unexplored. A multiomic approach was performed at different seed developmental stages of common bean (Phaseolus vulgaris L.) during asymptomatic colonization by Xanthomonas citri pv.
Armelle Darrasse+6 more
wiley +1 more source
Mismatch-specific thymine DNA glycosylase and DNA polymerase beta mediate the correction of G.T mispairs in nuclear extracts from human cells. [PDF]
K Wiebauer, Josef Jiricny
openalex +1 more source