Results 91 to 100 of about 38,912 (254)

Polyhexamethylene Biguanide and Nadifloxacin Self-Assembled Nanoparticles: Antimicrobial Effects against Intracellular Methicillin-Resistant Staphylococcus aureus [PDF]

, 2018
The treatment of skin and soft tissue infections caused by methicillin-resistant Staphylococcus aureus (MRSA) remains a challenge, partly due to localization of the bacteria inside the host’s cells, where antimicrobial penetration and efficacy is limited.
Chivu, A, de Fatima Pina, M, Good, L, Kamaruzzaman, N F   +3 more
core   +3 more sources

Synthesis of 2‐(Quinoxalin‐2‐yl)acetamides and Their Preliminary Cytotoxic and Antibacterial Activity

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT Quinoxaline is an aza‐heterocycle found in some bioactive compounds. Thus, to enhance the pharmacological scope of this nucleus, we report a series of 19 acetamides decorated with a quinoxaline core. The synthesis involved the linkage of previously constructed bromoacetamides and hydroxyphenyl quinoxalines via an SN2 reaction. The first series
Cesar E. Tovar‐Roman, Eduardo Hernández‐Vázquez, José A. Rivera‐Chávez   +2 more
wiley   +1 more source

Genomic transcriptional response to loss of chromosomal supercoiling in Escherichia coli [PDF]

, 2011
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'.
Arsuaga, Javier, Breier, Adam M, Brown, Patrick O, Cozzarelli, Nicholas R, Khodursky, Arkady B, Peter, Brian J   +5 more
core   +2 more sources

Emerging Biomedical Engineering Therapies for Infected Diabetic Foot Ulcers: Toward Antibacterial Functionalization and Pathology‐Responsive Regulation

Small Science, Volume 6, Issue 1, January 2026.
Infected diabetic foot ulcer endangers patients with high amputation, disability, mortality risks, and heavy medical burdens. This review analyzes its pathogenic factors, the limitations of current treatments, the breakthroughs of responsive antimicrobial biomaterials, and the challenge of multifunctional biomaterial innovations for further developing ...
Yaqi Yao, Mengyi Huang, Yuetong Li, Yiqi Lin, Junjie Dong, Jianhang Du, Aixia Zhai, Changlong Bi, Luoyuan Li   +8 more
wiley   +1 more source

Crystal structures of Thermotoga maritima reverse gyrase: inferences for the mechanism of positive DNA supercoiling [PDF]

, 2017
Reverse gyrase is an ATP-dependent topoisomerase that is unique to hyperthermophilic archaea and eubacteria. The only reverse gyrase structure determined to date has revealed the arrangement of the N-terminal helicase domain and the C-terminal ...
del Toro Duany, Yoandris, Ganguly, Agneyo, Jungblut, Stefan P., Klostermeier, Dagmar, Rudolph, Markus G.   +4 more
core  

Antimicrobial Efficacy of Garlic (Allium sativum) Extract Against Aeromonas Hydrophila Isolated From Diseased Pangasius Catfish

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
The study evaluated the antibacterial efficacy of garlic (Allium sativum) extracts against Aeromonas hydrophila isolated from diseased Pangasius catfish. Methanolic extract exhibited significant antibacterial activity, producing the largest inhibition zone (15.11 ± 0.05 mm) at 8 mg/mL and showing MIC and MBC values at 6–8 and 8 mg/mL, respectively. The
Sumaia Siddique, Md. Mubarack Hossain, Md. Nurul Haider   +2 more
wiley   +1 more source

SMC is recruited to oriC by ParB and promotes chromosome segregation in Streptococcus pneumoniae [PDF]

, 2011
Segregation of replicated chromosomes is an essential process in all organisms. How bacteria, such as the oval-shaped human pathogen Streptococcus pneumoniae, efficiently segregate their chromosomes is poorly understood.
Avery, Baerends, Bloom, Bouthier de la Tour, Britton, Dagkessamanskaia, Danilova, Eberhardt, Errington, Fadda, Ferrandiz, Fogel, Gasc, Gerdes, Glaser, Graumann, Gruber, Guthlein, Halfmann, Hendriksen, Hoskins, Hudson, Hui, Ireton, Jun, Jun, Katayama, Kloosterman, Kornberg, Lanie, Leenhouts, Lin, Lindow, Livny, Lynch, Martin, Mascarenhas, Mitchell, Moriya, Mott, Murray, Nasmyth, O'Brien, Onn, Ptacin, Reyes-Lamothe, Ringgaard, Salje, Sambrook, Schofield, Scholefield, Sebert, Soppa, Sullivan, Terzaghi, Thanbichler, Toro, van der Poll, Weiser, Yu, Zakrzewska-Czerwinska, Zhao   +61 more
core   +5 more sources

Computational Analysis of DNA Gyrase Action [PDF]

Biophysical Journal, 2004
DNA gyrase introduces negative supercoiling into circular DNA by catalyzing the passage of one DNA segment through another. The efficiency of the reaction is many times higher than that of other topological transformations. We analyze, by a computer simulation, the reaction selectivity for a model of DNA gyrase action that assumes existence of a free ...
openaire   +2 more sources

Antibiotic Resistance of Campylobacter Species Isolated From Foods, Animals and Humans in Iran Through One Health Approach: A Systematic Review and Meta‐Analysis

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
Forest plot of pooled prevalence/proportion of erythromycin resistance in Campylobacter coli (a) and C. jejuni (b). C. coli isolates (0.18) had twice resistance to erythromycin than C. jejuni isolates (0.09). ABSTRACT In this study, a systematic review and meta‐analysis were conducted to consider antimicrobial resistance (AMR) rates of Campylobacter in
Fatemeh Salmani, Sara Mohamadi, Taurai Tasara, Elham Ansarifar, Parisa Sadighara, Tayebeh Zeinali   +5 more
wiley   +1 more source

New rhenium complexes with ciprofloxacin as useful models for understanding the properties of [99mTc]-ciprofloxacin radiopharmaceutical [PDF]

, 2014
Rhenium complexes with the antibiotic ciprofloxacin have been prepared to be studied as models of technetium radiopharmaceuticals. With this aim, the new rhenium complexes 1 {[ReO(Cpf)2]Cl}, 2 {[ReO(CpfH)2]Cl3} and 3 {fac-[Re(CO)3(H2O)(Cpf)]} with ...
Cortés Garmendia, M. Pilar, Lecina, Joan, Llagostera Casas, Montserrat, Piera, Carlos, Suades Ortuño, Joan   +4 more
core   +2 more sources