Results 111 to 120 of about 19,626 (172)

Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms. [PDF]

Nat Chem Biol
Aleksandrova EV, Ma CX, Klepacki D, Alizadeh F, Vázquez-Laslop N, Liang JH, Polikanov YS, Mankin AS.   +7 more
europepmc   +1 more source

New Benzofuran-Pyrazole-Based Compounds as Promising Antimicrobial Agents: Design, Synthesis, DNA Gyrase B Inhibition, and In Silico Studies. [PDF]

Pharmaceuticals (Basel)
Abd El-Karim SS, Anwar MM, Syam YM, Awad HM, El-Dein AN, El-Ashrey MK, Alkahtani HM, Abdelwahed SH.   +7 more
europepmc   +1 more source

4-Quinolones and the Physiology of DNA Gyrase

, 1994
K, Drlica, B, Kreiswirth
openaire   +2 more sources

Synthesis and Antimicrobial Evaluation of New 1,2,4-Triazolo[1,5-a]pyrimidine-Based Derivatives as Dual Inhibitors of Bacterial DNA Gyrase and DHFR. [PDF]

ACS Omega
Al-Wahaibi LH, Rabea SM, Mahmoud MA, Youssif BGM, Bräse S, Abdel-Aziz SA.   +5 more
europepmc   +1 more source

Structural basis of DNA crossover capture by <i>Escherichia coli</i> DNA gyrase. [PDF]

Science
Vayssières M, Marechal N, Yun L, Lopez Duran B, Murugasamy NK, Fogg JM, Zechiedrich L, Nadal M, Lamour V.   +8 more
europepmc   +1 more source

New N-phenylpyrrolamide inhibitors of DNA gyrase with improved antibacterial activity. [PDF]

RSC Adv
Cotman AE, Fulgheri F, Piga M, Peršolja P, Tiz DB, Skok Ž, Durcik M, Sterle M, Dernovšek J, Cruz CD, Tammela P, Szili PÉ, Daruka L, Pál C, Zega A, Mašič LP, Ilaš J, Tomašič T, Kikelj D, Zidar N.   +19 more
europepmc   +1 more source

Signal Propagation in the ATPase Domain of Mycobacterium tuberculosis DNA Gyrase from Dynamical-Nonequilibrium Molecular Dynamics Simulations. [PDF]

Biochemistry
Kamsri B, Kamsri P, Punkvang A, Chimprasit A, Saparpakorn P, Hannongbua S, Spencer J, Oliveira ASF, Mulholland AJ, Pungpo P.   +9 more
europepmc   +1 more source

Identification of Anti-Tuberculosis Drugs Targeting DNA Gyrase A and Serine/Threonine Protein Kinase PknB: A Machine Learning-Assisted Drug-Repurposing Approach. [PDF]

Trop Med Infect Dis
Lee D, Islam MA, Natarajan S, Dudekula DB, Chung H, Park J, Oh B.   +6 more
europepmc   +1 more source

New N-amino-5-cyano-6-pyridones as antimicrobial small molecules endowed with DNA gyrase a inhibitory activity: design, one-pot synthesis, biological assessment and in silico insights. [PDF]

BMC Chem
Kamaly OA, Younes AS, Harras MF, Sabour R, Alsfouk AA, Ibrahim MH.   +5 more
europepmc   +1 more source

Ligand-Based Virtual Screening for Discovery of Indole Derivatives as Potent DNA Gyrase ATPase Inhibitors Active against Mycobacterium tuberculosis and Hit Validation by Biological Assays. [PDF]

J Chem Inf Model
Pakamwong B, Thongdee P, Kamsri B, Phusi N, Taveepanich S, Chayajarus K, Kamsri P, Punkvang A, Hannongbua S, Sangswan J, Suttisintong K, Sureram S, Kittakoop P, Hongmanee P, Santanirand P, Leanpolchareanchai J, Spencer J, Mulholland AJ, Pungpo P.   +18 more
europepmc   +1 more source