Results 41 to 50 of about 47,217 (278)
eLife, 2019 DNA replication requires that the duplex genomic DNA strands be separated; a function that is implemented by ring-shaped hexameric helicases in all Domains.
Himasha M Perera, Michael A Trakselis
doaj +1 more source
Use of streptavidin bound to biotinylated DNA structures as model substrates for analysis of nucleoprotein complex disruption by helicases [PDF]
, 2016 Helicases are a subfamily of translocases that couple the directional translocation along a nucleic acid lattice to the separation of nucleic acid duplexes using the energy derived from nucleoside triphosphate hydrolysis.
Brüning, Jan-Gert +2 more
core +1 more source
Helicase‐dependent isothermal DNA amplification [PDF]
EMBO reports, 2004 Polymerase chain reaction is the most widely used method for in vitro DNA amplification. However, it requires thermocycling to separate two DNA strands. In vivo , DNA is replicated by DNA polymerases with various accessory proteins, including a DNA ...
Myriam, Vincent, Yan, Xu, Huimin, Kong
openaire +2 more sources
iScience, 2022 Summary: I-motifs are noncanonical four-stranded DNA structures formed by C-rich sequences at acidic environment with critical biofunctions. The particular pH sensitivity has inspired the development of i-motifs as pH sensors and DNA motors in ...
Bo Gao +5 more
doaj +1 more source
Coupling of Two Motor Proteins: a New Motor Can Move Faster [PDF]
, 2005 We study the effect of a coupling between two motor domains in highly-processive motor protein complexes. A simple stochastic discrete model, in which the two parts of the protein molecule interact through some energy potential, is presented.
Anatoly B. Kolomeisky +8 more
core +1 more source
BMC Microbiology, 2012 Background Regulation of surface antigenic variation in Giardia lamblia is controlled post-transcriptionally by an RNA-interference (RNAi) pathway that includes a Dicer-like bidentate RNase III (gDicer).
Gargantini Pablo R +3 more
doaj +1 more source
The Human Replicative Helicase, the CMG Complex, as a Target for Anti-cancer Therapy
Frontiers in Molecular Biosciences, 2018 DNA helicases unwind or rearrange duplex DNA during replication, recombination and repair. Helicases of many pathogenic organisms such as viruses, bacteria, and protozoa have been studied as potential therapeutic targets to treat infectious diseases, and
Yeon-Soo Seo, Young-Hoon Kang
doaj +1 more source
Srs2 Disassembles Rad51 Filaments by a Protein-Protein Interaction Triggering ATP Turnover and Dissociation of Rad51 from DNA [PDF]
, 2009 Rad51 is a DNA recombinase functioning in the repair of DNA double-strand breaks and the generation of genetic diversity by homologous recombination (HR).
Antony, Edwin +5 more
core +2 more sources
Unraveling DNA helicases [PDF]
European Journal of Biochemistry, 2004 DNA helicases are molecular ‘motor’ enzymes that use the energy of NTP hydrolysis to separate transiently energetically stable duplex DNA into single strands. They are therefore essential in nearly all DNA metabolic transactions. They act as essential molecular tools for the cellular machinery.
Narendra, Tuteja, Renu, Tuteja
openaire +2 more sources
Frontiers in Cell and Developmental BiologyRNA helicases are enzymes that remodel RNA secondary structures and RNA-protein complexes using ATP-driven motor forces. They are known to participate in many essential cellular processes, including transcription, splicing, translation, RNA decay, and ...
Katherine Herrera +3 more
doaj +1 more source