The CIC::DUX4 oncoprotein maintains DNA integrity through direct regulation of the catalytic subunit of DNA polymerase epsilon (POLE). [PDF]
Kosibaty Z, Luck C, Okimoto RA.
europepmc +1 more source
Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon +5 more
wiley +1 more source
Repeatome Analysis of Plasma Circulating DNA in Patients with Cardiovascular Disease: Variation with Cell-Free DNA Integrity/Length and Clinical Parameters. [PDF]
Fumarola S +9 more
europepmc +1 more source
Electrostatic Superlattices Beyond 1:1 Stoichiometry
Polymer‐mediated charge regulation drives two hierarchical routes to higher‐stoichiometry nanoparticle superlattices. Tuning the polymer's molecular weight promotes progressive interstitial filling, transforming ZnS into the fully occupied CaF2${\rm CaF}_2$ lattice. Exchanging polymer assignment between large and small nanoparticles instead breaks CsCl
Binay P. Nayak +7 more
wiley +1 more source
Increasing age in men is negatively associated with sperm quality and DNA integrity but not pregnancy outcomes in assisted reproductive technology. [PDF]
Xie H +6 more
europepmc +1 more source
Reversible Tuning of Multiple Molecular Kinking for Stem Cell Regulation In Vivo
In this work, we introduce the novel concept of background component‐free “multiple kinks” material platform composed solely of liganded multiple kink‐bearing molecules as a strategy for dynamic biomaterial design. Tri‐kink molecules enable effective near‐infrared light‐triggered ligand masking and visible light‐triggered ligand exposure, thereby ...
Kanghyeon Kim +28 more
wiley +1 more source
Pan-cancer genetic profiles of mitotic DNA integrity checkpoint protein kinases. [PDF]
Rasteh AM, Liu H, Wang P.
europepmc +1 more source
Causal Inference Approaches Reveal Associations Between LDL Oxidation, NO Metabolism, Telomere Length and DNA Integrity Within the MARK-AGE Study. [PDF]
Valeanu A +30 more
europepmc +1 more source
Correction to "Sperm Selection Using Cumulus Cell Column Improves Sperm DNA Integrity, Embryo Morphokinetics, and Clinical Outcomes Following ICSI: A Randomized Clinical Trial". [PDF]
europepmc +1 more source
Temperatures Lower than Preferred Ones Maintain DNA Integrity and Sperm Quality of <i>Lepidophyma gaigeae</i> (SQUAMATA: XANTUSIIDAE). [PDF]
Uriostegui Escoto D +4 more
europepmc +1 more source

