Results 171 to 180 of about 2,162,763 (370)

Control of human adenovirus type 5 gene expression by cellular Daxx/ATRX chromatin-associated complexes [PDF]

, 2013
Death domain–associated protein (Daxx) cooperates with X-linked α-thalassaemia retardation syndrome protein (ATRX), a putative member of the sucrose non-fermentable 2 family of ATP-dependent chromatin-remodelling proteins, acting as the core ATPase ...
Andreas Mund, Badens, Baker, Berk, Berube, Blanchette, Carolin Bürck, Chatterjee, Cheng, Chinnadurai, Cuchet-Lourenco, Dallaire, Dellaire, Dobner, Drane, Everett, Flint, Frisch, Gibbons, Glass, Goldberg, Goldberg, Gostissa, Graham, Groitl, Gunther, Hancock, Harlow, Hassan, Hollenbach, Ishov, Ishov, Jin, Kahyo, Kindsmuller, Kindsmuller, Kindsmüller, Ko, Komatsu, Kosulin, Lewis, Lewis, Li, Lukashchuk, Lukashchuk, Mandy Glass, Marton, Matsumoto, Maul, McFarlane, Michaelson, Mitsudomi, Mund, Nevels, Nevins, Nevins, Niforou, Okuwaki, Orazio, Parks, Pelka, Peter Groitl, Peter Wimmer, Placek, Querido, Roger D. Everett, Ross, Rubenwolf, Sabrina Schreiner, Salomoni, Sarah Kinkley, Sarnow, Schreiner, Schreiner, Schreiner, Shenk, Si, Song, Stracker, Takahashi, Tang, Thomas Dobner, Torii, Täuber, Täuber, Ullman, White, Williams, Wilson, Wong, Wong, Xu, Xue   +92 more
core   +1 more source

Sealing of gaps in duplex DNA by T4 DNA ligase

Nucleic Acids Research, 1982
Single-strand gaps in DNA molecules were found to be a substrate for T4 DNA ligase. Sealing of the gaps was optimal at the same conditions as ligation of blunt-ended DNA molecules. Spermidine at a concentration of 2 mM stimulated the ligation of gaps, as well as the joining of DNA molecules with cohesive and blunt ends.
Göran Magnusson, Stefan Nilsson
openaire   +4 more sources

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

Advanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang, Xing Chang, Chun Li, Jing Gao, Zhijiang Guo, Haowen Zhuang, Lingjun Wang, Yusheng Huang, Wei Wang, Chao Li, Qingyong He   +10 more
wiley   +1 more source

DNA insertion mutations can be predicted by a periodic probability function [PDF]

arXiv, 2017
It is generally difficult to predict the positions of mutations in genomic DNA at the nucleotide level. Retroviral DNA insertion is one mode of mutation, resulting in host infections that are difficult to treat. This mutation process involves the integration of retroviral DNA into the host-infected cellular genomic DNA following the interaction between
arxiv  

Enzymatic breakage and joining of deoxyribonucleic acid. IV. DNA synthesis in E. coli infected with ligase-negative mutants of phage T4. [PDF]

, 1968
Yukito Masamune, C C Richardson
openalex   +1 more source

DNA repair: Disorders [PDF]

, 2010
No description ...
Bose, Burg, Caldecott, Chu, Digweed, Fernandez-Capetillo, Fousteri, Fousteri, Friedberg, Gudmundsdottir, Hashimoto, Hoeijmakers, Jiricny, Kraemer, Lavin, Lehmann, Lieber, Ma, Masutani, McCulloch, Meindl, Moldovan, Moshous, Nance, Nouspikel, O'Driscoll, O'Driscoll, O'Driscoll, O'Driscoll, Rass, Stefanini, Stewart, Stracker, Taylor, Vaz, Wu, Zlatanou   +36 more
core   +1 more source

Meisoindigo Acts as a Molecular Glue to Target PKMYT1 for Degradation in Chronic Myeloid Leukemia Therapy

Advanced Science, EarlyView.
Meisoindigo targets PKMYT1 for degradation by acting as a molecular glue that enhances PKMYT1‐TRIM25 interaction, leading to K48‐linked ubiquitination and subsequent proteasomal degradation, thereby exerting therapeutic effects in chronic myeloid leukemia.
Zhao‐Xin Zhang, Shu‐Ying Li, Fang‐Fei Li, Qin‐Yan Shi, Cheng‐Yong Tan, Xiao‐Jing Wang, Mi Li, Yun‐Bao Liu, Jing Jin, Yong Li, Shi‐Shan Yu   +10 more
wiley   +1 more source

Strukturaufklärung, Totalsynthese, In‐Vivo‐Aktivität und Potentieller Biosyntheseweg des Neuen Myxobakteriellen Antibiotikums Corramycin**

Angewandte Chemie, Volume 134, Issue 51, December 19, 2022., 2022
Corramycin ist ein neuer Naturstoff, welcher von dem Myxobakterium Corallococcus coralloides produziert wird. Seine Struktur sowie die außergewöhnliche Total‐ und Biosynthese des Antibiotikums werden hier zum ersten Mal beschrieben. Corramycin zeigt keine Zytotoxizität und keine Kreuzresistenz mit gängigen Antibiotikaklassen.
Cédric Couturier, Sebastian Groß, Alexander von Tesmar, Judith Hoffmann, Selina Deckarm, Anouchka Fievet, Nelly Dubarry, Thomas Taillier, Christoph Pöverlein, Heike Stump, Michael Kurz, Luigi Toti, Sabine Haag Richter, Dietmar Schummer, Philippe Sizun, Michael Hoffmann, Ram Prasad Awal, Nestor Zaburannyi, Kirsten Harmrolfs, Joachim Wink, Emilie Lessoud, Thierry Vermat, Veronique Cazals, Sandra Silve, Armin Bauer, Michael Mourez, Laurent Fraisse, Corinne Leroi‐Geissler, Astrid Rey, Stéphanie Versluys, Eric Bacqué, Rolf Müller, Stephane Renard   +32 more
wiley   +1 more source

MicroRNA-300 Regulates the Ubiquitination of PTEN through the CRL4BDCAF13 E3 Ligase in Osteosarcoma Cells

Molecular Therapy: Nucleic Acids, 2018
Cullins, critical members of the cullin-RING ubiquitin ligases (CRLs), are often aberrantly expressed in different cancers. However, the underlying mechanisms regarding aberrant expression of these cullins and the specific substrates of CRLs in different
Zhi Chen, Wei Zhang, Kaibiao Jiang, Bin Chen, Kun Wang, Lifeng Lao, Canglong Hou, Fei Wang, Caiguo Zhang, Hongxing Shen   +9 more
doaj   +1 more source

The Art of DNA Strings: Sixteen Years of DNA Coding Theory [PDF]

arXiv, 2016
The idea of computing with DNA was given by Tom Head in 1987, however in 1994 in a seminal paper, the actual successful experiment for DNA computing was performed by Adleman. The heart of the DNA computing is the DNA hybridization, however, it is also the source of errors.
arxiv