Results 191 to 200 of about 79,069 (319)
Gigaxonin Potentiates Antiviral Innate Immune Responses by Targeting cGAS and TREX1
Advanced Science, EarlyView.TREX1 antagonizes DNA sensor cGAS by degrading cytosolic DNA. This work identifies gigaxonin as a molecular switch that coordinates DNA sensing and clearance pathways to amplify antiviral responses. Under the steady state, gigaxonin maintains cellular homeostasis by mediating TREX1 ubiquitination and proteasomal degradation. During DNA virus infection,
Ben‐Zhe Ji +9 more
wiley +1 more source
Is the detection of Mycobacterium tuberculosis DNA by ligase chain reaction worth the cost: experiences from an inner London teaching hospital [PDF]
, 2000 Nandini Shetty
openalex +1 more source
Advanced Science, EarlyView.This figure is a candidate for the cover image. It shows a whole‐mount fluorescent image of lymphatic vessels (red) in the heart of an adult Cdh5‐Dre; Prox1‐RSR‐CreER; Rosa26‐tdT mouse. Image courtesy of Ximeng Han. Abstract Cell fate determination is a fundamental process in multicellular development.
Hui Chen +3 more
wiley +1 more source
Rsp5, a Ubiquitin-Protein Ligase, Is Involved in Degradation of the Single-Stranded-DNA Binding Protein Rfa1 in Saccharomyces cerevisiae [PDF]
, 2000 Naz Erdeniz, Rodney Rothstein
openalex +1 more source
CDH1 Orchestrates Anabolic Events to Promote Cell Cycle Initiation
Advanced Science, EarlyView.Cell proliferation requires the integration of cell cycle and anabolic signals. G1‐phase regulator CDH1 coordinates anabolism through the CDH1‐VHL‐AARS2/HIF1α axis, while CDH1‐accumulated R5P is sensed by TKTL1 to facilitate CDH1 degradation and cell cycle initiation, constituting a CDH1‐centered regulatory circuit.
Yun‐Zi Mao +18 more
wiley +1 more source
Polynucleotide 3'-terminal phosphate modifications by RNA and DNA ligases. [PDF]
J Biol Chem, 2014 Zhelkovsky AM, McReynolds LA.
europepmc +1 more source
Head inactivation of DNA ligase prior to electroporation increases transformation efficiency
, 1991 S. Ymer
openalex +2 more sources
Crystal structure of NAD+-dependent DNA ligase: modular architecture and functional implications [PDF]
, 2000 Jae Young Lee +7 more
openalex +1 more source