Results 201 to 210 of about 53,303 (248)

Mechanisms and Design Principles of Proteolysis-Targeting Chimeras and Their Emerging Applications. [PDF]

ACS Pharmacol Transl Sci
Knoll N, Neamati N, Üren A.
europepmc   +1 more source

Investigations of the Evolved Molecular Basis for Terpenoid Biosynthesis in Marine Sponges

Advanced Science, EarlyView.
Confirming and extending a previous observation in another Bubarida sponge, genomic and functional analyses of A. cavernosa reveal that sponges retain the mevalonate pathway and employ single α‐domain T1TSs and UbiA‐type TSs for terpenoid biosynthesis. The absence of T1TSs clustering with other biosynthetic genes tentatively suggests, based on limited ...
Fangyan Chen, Bao Chen, Wenhui Zhang, Guifang Sun, Yao Zhao, Jianpeng Zhang, Baofu Xu   +6 more
wiley   +1 more source

Ubiquitylation and Deubiquitylation in Health and Diseases. [PDF]

Biomedicines
Nakagawa T.
europepmc   +1 more source

A special issue of Essays in Biochemistry on proteasome and protein degradation. [PDF]

Essays Biochem
Sahu I, Glickman MH.
europepmc   +1 more source

The role of e3 ubiquitin ligases and deubiquitinating enzymes in hepatocellular carcinoma. [PDF]

Cell Biol Toxicol
Wang L, Zhang H, Hu Y, Li X, Liu J, Liang Y.   +5 more
europepmc   +1 more source

Regulatory mechanisms for Snail protein stability: ubiquitin-proteasome system and chaperone-mediated autophagy. [PDF]

Exp Mol Med
Kim M, Hong KS, Kim T, Ryu KJ, Yoo J.
europepmc   +1 more source

Time- and space-resolved transcriptional regulation in Arabidopsis thaliana. [PDF]

Plant Biol (Stuttg)
Zenker S, Schiller K, Bräutigam A.
europepmc   +1 more source

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Eukaryotic DNA ligases

Mutation Research DNA Repair, 1990
Recent studies on eukaryotic DNA ligases are briefly reviewed. The two distinguishable enzymes from mammalian cells, DNA ligase I and DNA ligase II, have been purified to homogeneity and characterized biochemically. Two distinct DNA ligases have also been identified in Drosophila melanogaster embryos.
Alan Tomkinson, T Lindahl, Tomáš Lindahl   +2 more
exaly   +3 more sources

DNA ligases in the repair and replication of DNA

Mutation Research DNA Repair, 2000
DNA ligases are critical enzymes of DNA metabolism. The reaction they catalyse (the joining of nicked DNA) is required in DNA replication and in DNA repair pathways that require the re-synthesis of DNA. Most organisms express DNA ligases powered by ATP, but eubacteria appear to be unique in having ligases driven by NAD(+).
Dale Wigley, David J Timson
exaly   +3 more sources