Results 201 to 210 of about 2,144,804 (323)

Targeted polyubiquitylation of RASSF1C by the Mule and SCF β-TrCP ligases in response to DNA damage

, 2020
Xin Zhou, Tingting Li, Feng Xu, Esther Y. Hsiang, Yue Xiong, Kun‐Liang Guan, Qun‐Ying Lei   +6 more
openalex   +1 more source

Cellular DNA Ligase I Is Recruited to Cytoplasmic Vaccinia Virus Factories and Masks the Role of the Vaccinia Ligase in Viral DNA Replication [PDF]

, 2009
Nir Paran, Frank S. De Silva, Tatiana G. Senkevich, Bernard Moss   +3 more
openalex   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage

, 2007
Bin Wang, Stephen J. Elledge
openalex   +2 more sources

Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV [PDF]

, 1997
Susan E. Critchlow, Richard P. Bowater, Stephen P. Jackson   +2 more
openalex   +1 more source

CSN6 Promotes Pancreatic Cancer Progression and Gemcitabine Resistance via Antagonizing DCAF1‐Mediated Ubiquitination of NPM1

Advanced Science, EarlyView.
COP9 signalosome subunit 6 (CSN6) promotes the auto‐ubiquitination and degradation of DDB1‐CUL4 associated factor 1 (DCAF1), thereby antagonizing DCAF1‐mediated ubiquitination of Nucleophosmin (NPM1). This stabilization of NPM1 enhances the ribosome biogenesis process and the translation of specific gemcitabine‐resistance proteins, ultimately driving ...
Yijing Zhang, Han Gao, Aiwen Tang, Haiwen Lyu, Zongmin Fan, Jiahui Guo, Yuzhi Wang, Hairong Yi, Qihao Pan, Haidan Luo, Baifu Qin, Boyu Zhang, Xiangqi Meng, Qingxin Liu, Mong‐Hong Lee   +14 more
wiley   +1 more source

AP Endonuclease 1 Coordinates Flap Endonuclease 1 and DNA Ligase I Activity in Long Patch Base Excision Repair

, 2002
Tamara A. Ranalli, Samson Tom, Robert A. Bambara   +2 more
openalex   +1 more source

Two Distinct DNA Ligase Activities in Mitotic Extracts of the Yeast Saccharomyces Cerevisiae [PDF]

, 1997
William Ramos, Nancy J. Tappe, J. Talamantez, E C Friedberg, A. E. Tomkinson   +4 more
openalex   +1 more source

Mammalian DNA ligases.

Annual Review of Biochemistry, 1992
Tomas Lindahl, D. Barnes
semanticscholar   +1 more source

Ubc9‐Mediated SUMOylation of RPL3, an Unappreciated Mechanism against Hepatocyte Senescence by Repressing the DHX9‐p16 Axis

Advanced Science, EarlyView.
Liver aging is characterized by a decline in the expression of the SUMO‐conjugating enzyme Ubc9, resulting in reduced SUMOylation levels in hepatocytes, particularly in the case of ribosomal protein RPL3. Disruption of RPL3 SUMOylation increases its nuclear translocation. Interestingly, ribosome‐free RPL3 facilitates the recruitment of helicase DHX9 to
Hao Xie, Zhichao Gao, Xin Liu, Shiyi Zhang, Yuhan Wang, Jia Gao, Ping Qi, Lu Zhang, Jiawei Zhao, Tian Xiong, Teng Huang, Jia Song, Qilin Yu, Shu Zhang, Yanjun Liu, Ping Yang, Maryam S. Al‐Motawa, Quan Gong, Junfeng Dong, Hao Yin, Fei Sun, Shiwei Liu, Cong‐Yi Wang   +22 more
wiley   +1 more source