Results 211 to 220 of about 2,144,804 (323)

Effects of Adrenaline, Cortisone, Glucose Oxime, N-methyl-N'-nitro-N-nitrosoguanidine and Mitomycin C on DNA Polymerase and DNA Ligase [PDF]

, 1977
Satoru Iiyama, Hirohisa Omura, Hiroki Murakami, Yoko Narazaki, K Yamafuji   +4 more
openalex   +1 more source

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source

Inhibition of TOPORS ubiquitin ligase augments the efficacy of DNA hypomethylating agents through DNMT1 stabilization

Satoshi Kaito, Kazumasa Aoyama, Motohiko Oshima, Akiho Tsuchiya, Makiko Miyota, Masayuki Yamashita, Shuhei Koide, Yaeko Nakajima-Takagi, Hiroko Kozuka‐Hata, Masaaki Oyama, Takao Yogo, Tomohiro Yabushita, Ryoji Ito, Masaya Ueno, Atsushi Hirao, Kaoru Tohyama, Chao Li, Kimihito C. Kawabata, Kiyoshi Yamaguchi, Yoichi Furukawa, Hidetaka Kosako, Akihide Yoshimi, Susumu Goyama, Yasuhito Nannya, Seishi Ogawa, Karl Agger, Kristian Helin, Satoshi Yamazaki, Haruhiko Koseki, Noriko Doki, Yuka Harada, Hironori Harada, Atsuya Nishiyama, Makoto Nakanishi, Atsushi Iwama   +34 more
openalex   +1 more source

Regulation of various DNA repair pathways by E3 ubiquitin ligases

, 2017
Chandramouli Natarajan, Ken’ichi Takeda   +1 more
openalex   +1 more source

MSC Membrane‐Coated circPROSC‐siRNA Nanoparticles for Ameliorating Craniosynostosis by Inhibiting Premature Suture Ossification

Advanced Science, EarlyView.
CircPROSC promotes craniosynostosis by sponging miR‐6815‐5p, thereby activating WNT3A/β‐catenin signaling and enhancing RUNX2‐mediated osteogenesis. Targeted silencing of circPROSC with MSC membrane–coated siRNA nanoparticles (MM@Lipo/si‐circPROSC) delivered postnatally into cranial sutures attenuates premature suture closure in Twist1+/– mice ...
Zhenkun Weng, Xiu Chen, Jin Xu, Qing Yan, Jian Jiao, Qian Liu, Aihua Gu   +6 more
wiley   +1 more source

Specific isoforms of the ubiquitin ligase gene WWP2 are targets of osteoarthritis genetic risk via a differentially methylated DNA sequence [PDF]

Jack B. Roberts, Olivia Lucy Georgina Boldvig, Guillaume Aubourg, Sai Tanishq Kanchenapally, David J. Deehan, Sarah J. Rice, John Loughlin   +6 more
openalex   +1 more source

Effects of DNA end configuration on XRCC4-DNA ligase IV and its stimulation of Artemis activity [PDF]

, 2017
C.A. Gerodimos, Howard H. Chang, Go Watanabe, Michael R. Lieber   +3 more
openalex   +1 more source

Identification and characterization of an inhibitor specific to bacterial NAD+‐dependent DNA ligases

The FEBS Journal, 2008
T. Meier, D. Yan, R. Peery, K. A. McAllister, C. Zook, Sheng-Bin Peng, Genshi Zhao   +6 more
semanticscholar   +1 more source

Site‐Specific Mitochondrial RNA N1‐Methyladenosine Demethylation via an Engineered MTS‐PUF‐ALKBH3 Fusion Protein

Advanced Science, EarlyView.
A CRISPR‐free mitochondrial RNA m1A demethylation (MRD) editor combining MTS, PUF proteins, and ALKBH3 enables precise m1A removal from mitochondrial mRNA and tRNA, which influences mitochondrial protein levels, cellular proliferation, ATP production, and mitochondrial respiration. Subsequently, in vivo demethylation of the m1A modification is achieved
Xiangrui Li, Deqiang Kong, Hongmei Liu, Jie Yang, Jiale Zhou, Yuqiang Qian, Ding Zhao, Jinze Li, Xinyu Wu, Tao Zhang, Xiaodi Sun, Yang Han, Liangxue Lai, Zhanjun Li   +13 more
wiley   +1 more source

Rat liver DNA ligases [PDF]

, 1992
Rhoderick H. Elder, Alessandra Montecucco, Giovanni Ciarrocchi, Jean‐Michel Rossignol   +3 more
openalex   +1 more source