Results 91 to 100 of about 2,394,908 (263)
Advanced Science, EarlyView.In this work, we present a bile‐based memristor hardware framework that enables direct, label‐free identification of cholelithiasis and gallbladder cancer at the device level. The Ag/bile/FTO memristor features stable resistive switching and disease‐specific electrical responses, providing a conceptual foundation for circuits and an integrated ERCP ...
Junming Zhu +17 more
wiley +1 more source
DNA Logic Gate Based on Metallo-Toehold Strand Displacement
PLoS ONE, 2014 DNA is increasingly being used as an ideal material for the construction of nanoscale structures, circuits, and machines. Toehold-mediated DNA strand displacement reactions play a very important role in these enzyme-free constructions. In this study, the concept of metallo-toehold was utilized to further develop a mechanism for strand displacement ...
Wei Deng +3 more
openaire +4 more sources
July 2002 Logic Gates made with DNA
, 2008 : The first step to construct molecular computational systems is to be able to develop simple units. The possibility of making logic gates with DNA (DeoxyriboNucleic Acid) means that we are not so far to reach this objective.
Work Dr +3 more
core
Erasable and Field Programmable DNA Circuits Based on Configurable Logic Blocks
Advanced ScienceDNA is commonly employed as a substrate for the building of artificial logic networks due to its excellent biocompatibility and programmability. Till now, DNA logic circuits are rapidly evolving to accomplish advanced operations.
Yizhou Liu +11 more
doaj +1 more source
Orthogonal Light‐ and Enzyme‐Triggered and‐Gate Prodrugs for Senolytic Therapy
Advanced Science, EarlyView.An orthogonal AND‐gate prodrug platform combines 390 nm near‐UV photocleavage with SA‐β‐gal activation to control payload release in senescent cells. Its modular architecture enables 4‐MU fluorescence, doxorubicin‐mediated cytotoxicity, and ARV‐771‐driven BRD4 degradation, supporting stimulus‐controlled senolytic design in cellular and organoid models.
Mengyang Chang +12 more
wiley +1 more source
Effect of Variability in SWCNT-Based Logic Gates
, 2009 This work is concerned with Carbon Nanotube diameter variations and the resulting uncertainties on the behavior of logic gates made from Single Walled Carbon Nanotubes (SWCNTs).
Ahmadi, Arash +2 more
core +1 more source
Advanced Science, EarlyView.By integrating knowledge‐augmented artificial intelligence with an oxygen‐supplemented 3D screening platform, a synergistic interaction between berberine and enzalutamide is identified. The framework integrates compound mechanisms of action with disease‐relevant signaling context to prioritize candidate combinations and generate testable pathway‐based ...
Chih‐Hui Lo +15 more
wiley +1 more source
Advanced Science, EarlyView.A low‐density lipoprotein receptor‐oriented biomimetic nanoplatform couples brain‐tumor delivery with a mechanistically matched regorafenib‐erythrodiol combination. Concurrent disruption of autophagic nutrient salvage and cholesterol homeostasis collapses bioenergetic and signaling support, suppresses glioblastoma stemness, and promotes immunogenic ...
Yining Jiang +12 more
wiley +1 more source
Wallace Tree Multiplier Design and Simulation with DNA Logic Gates [PDF]
, 2016 The DNA molecule is indubitably the most powerful medium known to code, store information as a means of data storage but till now, DNA molecule has found little use in computing applications.
V M, Seeja, Raj A, Daniel, Deb, Sanjoy
core
Advanced Science, EarlyView.Schematic illustration of the CALCas system, in which a conformational switch in the 3' terminal DNA extension of scaffold RNA (3'D‐SR) drives cascade‐activatable Cas12a cleavage while suppressing leakage. ABSTRACT Amplification‐free CRISPR detection has attracted significant attention for its capacity to circumvent the intricacies of nucleic acid ...
Xingrong Li +11 more
wiley +1 more source