Results 131 to 140 of about 2,394,908 (263)

From Proxies to System State: Defining Sustainability Management Against Symbolic Progress

open access: yesSustainable Development, EarlyView.
ABSTRACT Sustainability in management is often measured through scores, ratings, and disclosure narratives that can reward symbolic progress while leaving underlying social‐ecological conditions unchanged. This perspective paper offers a definition of Sustainability Management as how organizations plan, organize, lead, and control (four management ...
Zhang Yiping, Olaf Weber
wiley   +1 more source

Tailoring Plasmonic Metamaterials for DNA Molecular Logic Gates

open access: yes, 2013
Structural and functional information encoded in DNA combined with unique properties of nanomaterials could be of use for the construction of novel biocomputational circuits and intelligent biomedical nanodevices.
Xu, Xinlong   +6 more
core   +2 more sources

From accidents to assets—The value pathways of patents for serendipitous inventions

open access: yesStrategic Management Journal, EarlyView.
Abstract Research Summary Firms often celebrate accidental inventions that lead to major breakthroughs, yet little is known about how the value of serendipitous inventions materializes. Using data from 8530 patented inventions across 23 countries, our research shows that these inventions differ from planned R&D outcomes.
Christoph Grimpe   +3 more
wiley   +1 more source

Mechanism‐Guided Engineering of Upconversion Nanoparticles for Antibacterial Phototherapy: From Photonic Principles to Translational Nanosystems

open access: yesSmall, EarlyView.
This review provides a systematic overview of the field of antibacterial PhotoDynamic Therapy (aPDT) triggered by upconversion nanoparticles (UCNPs), focusing on the mechanisms and the key factors that define their efficacy for generating bactericidal species upon NIR‐light activation.
Zhe Li   +3 more
wiley   +1 more source

Tailored Molecular Scissor Unlocks the Autocatalytic Potential of Hybridization Chain Reaction for Tunable Signal Amplification

open access: yesSmall, EarlyView.
We establish a recycling chain reaction (RCR) using a single hairpin, H3, which disassembles HCR assemblies to unlock the inherent autocatalytic potential of HCR. Conventional HCR is redefined as the fully constrained state (H3 = 0) of RCR. Tuning H3 ratios enables dynamic control over DNA assembly, providing a compact platform for biomolecular ...
Ting Li   +5 more
wiley   +1 more source

A Cytoplasmic pH Sensor Redefines Gating in Bacterial Urea Channels and Acid Resistance

open access: yesSmall, EarlyView.
Bacterial survival in acidic environments requires pH‐gated urea channels. Utilizing complementary approaches, we identify a conserved cytoplasmic glutamic acid residue as a pH sensor in UreI channels. Whereas Gram‐positive bacteria rely solely on this sensor, Gram‐negative bacteria employ a dual‐sensor mechanism with periplasmic residues, revealing a ...
Anna Stoib   +10 more
wiley   +1 more source

Machine Learning for Programmable Nanosystems: From Liposome Formulation to DNA Origami and Hybrid Vesicles

open access: yesSmall, EarlyView.
This mini review highlights how machine learning can accelerate the design of programmable nanosystems. It summarizes data‐driven approaches for predicting liposome properties, guiding DNA origami design and image analysis, and optimizing emerging liposome‐DNA hybrid platforms.
Daniel Q. Zhang, Matthew A. B. Baker
wiley   +1 more source

Synthetic Cells With Chemo‐Optical Signaling Enable Targeted Capture and Killing of Bacteria

open access: yesSmall, EarlyView.
The here presented synthetic cells capture bacteria through their internally produced bioluminescence signal and light activated adhesions. Subsequently, they eliminate the captured bacteria in through a locally elevated hydrogen peroxide concentration generated by membrane bound enzyme.
Xiaoran Zheng   +4 more
wiley   +1 more source

Biomaterial Platforms for Spatiotemporal Control of mRNA Delivery in Tissue Engineering and Regenerative Medicine: Design Rules, Therapeutic Applications, and Translational Roadmap

open access: yesSmall, EarlyView.
Biomaterial platforms can control where and when mRNA‐encoded proteins are expressed to support tissue repair. This Review proposes a cargo–target–timing framework linking therapeutic function, target tissues and cells, and expression profiles with carrier and scaffold design.
Huachun Pan   +14 more
wiley   +1 more source

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