Results 131 to 140 of about 2,256,913 (199)

From Proxies to System State: Defining Sustainability Management Against Symbolic Progress

Sustainable Development, EarlyView.
ABSTRACT Sustainability in management is often measured through scores, ratings, and disclosure narratives that can reward symbolic progress while leaving underlying social‐ecological conditions unchanged. This perspective paper offers a definition of Sustainability Management as how organizations plan, organize, lead, and control (four management ...
Zhang Yiping, Olaf Weber
wiley   +1 more source

From accidents to assets—The value pathways of patents for serendipitous inventions

Strategic Management Journal, EarlyView.
Abstract Research Summary Firms often celebrate accidental inventions that lead to major breakthroughs, yet little is known about how the value of serendipitous inventions materializes. Using data from 8530 patented inventions across 23 countries, our research shows that these inventions differ from planned R&D outcomes.
Christoph Grimpe, Karin Hoisl, Myriam Mariani, Wolfgang Sofka   +3 more
wiley   +1 more source

Hoberman‐Inspired Reconfigurable DNA Origami Ring for Nanoscale Capture

Small, EarlyView.
A Hoberman‐inspired DNA origami ring with coupled scissor‐like motion is designed and assembled. Reversible reconfiguration produces different conformations for organization of gold nanoparticles and capture of DNA nanostructures with varied sizes and geometries. ABSTRACT Dynamic DNA origami systems have enabled programmable nanoscale motion and target‐
Henry Wisniewski, Minu Saji, Moisés Reyes, Qi Yang, Fei Zhang   +4 more
wiley   +1 more source

Mechanism‐Guided Engineering of Upconversion Nanoparticles for Antibacterial Phototherapy: From Photonic Principles to Translational Nanosystems

Small, EarlyView.
This review provides a systematic overview of the field of antibacterial PhotoDynamic Therapy (aPDT) triggered by upconversion nanoparticles (UCNPs), focusing on the mechanisms and the key factors that define their efficacy for generating bactericidal species upon NIR‐light activation.
Zhe Li, Calum Johnston, Barbara Lonetti, Clément Roux   +3 more
wiley   +1 more source

White light emitting molecular logic gates

Smart Molecules, EarlyView.
White light emitting smart molecules with Boolean logic computing ability are surveyed. Abstract White light emitting (WLE) materials are of considerable interest with commercial and societal applications in video displays and lighting devices. A characteristic property of WLE materials is the luminescence profile spanning from 380 to 700 nm.
Davide Benedetto Tiz, Massimo Catania, David C. Magri   +2 more
wiley   +1 more source

Enhanced through‐bond energy transfer‐based bioorthogonal probe enables catalytic‐amplified and sensitive detection of microRNA‐21 for clinical lung cancer diagnosis

Smart Molecules, EarlyView.
Inverse Diels‐Alder Cycloaddition Reaction was developed for ultrasensitive miR‐21 detection. Based on the enhanced Through‐Bond Energy Transfer and catalytic amplification, it shows a detection limit of 3.58 × 10−18 M and 100 aM–100 nM linear range. It enables high‐contrast cell/tissue imaging and distinguishes lung cancer patients in serum, promising
Yikun Li, Fuping Han, Haiqiao Huang, Danhong Zhou, Saran Long, Wen Sun, Jianjun Du, Jiangli Fan, Jing Ning, Chong Peng, Xiaojun Peng   +10 more
wiley   +1 more source

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

Smart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin, Rui Peng, Guangshuai Zhang, Si Yan, Jin Xiao, Zishu Liu, Ziyu Tan, Qingqing Xie, Shangjie Li, Wei Luo, Xiaohe Xiao   +10 more
wiley   +1 more source

Harnessing the nonthermal effects of ultrasound for cancer treatment: From mechanisms to applications

Smart Molecules, EarlyView.
Nonthermal ultrasound transforms acoustic energy into diverse therapeutic bioeffects through cavitation, mechanical stimulation, and physicochemical activation. This review discusses how acoustic parameters, biological mechanisms, and responsive materials interact to influence nonthermal ultrasound‐enabled cancer therapies. Mechanism‐guided engineering
Liu Wang, Huan Tang, Yue Pan, Mingle Li, Weijie Zhao, Kai Liu   +5 more
wiley   +1 more source

Tailoring Plasmonic Metamaterials for DNA Molecular Logic Gates

, 2013
Structural and functional information encoded in DNA combined with unique properties of nanomaterials could be of use for the construction of novel biocomputational circuits and intelligent biomedical nanodevices.
Xu, Xinlong, Cao, Cuong; id_orcid, Tan, PingHeng, Liow, Chihao, Xiong, Qihua, Shuzhou, Li, Zhang, Jun   +6 more
core   +1 more source

Smart mesoporous silica nanoparticles for precision cancer therapy: Tumor targeting and stimuli‐responsive controlled release

Smart Molecules, EarlyView.
Smart mesoporous silica nanoparticles integrate tunable pore structures, molecular gates, targeting ligands, and stimuli‐responsive components to achieve controlled drug release for precision cancer therapy. This review highlights design principles, therapeutic applications, and future directions in immunotherapy, biodegradability, biosafety, and ...
Majdi Al‐Amili, Lei Lei, Zhu Jin
wiley   +1 more source