Results 211 to 220 of about 382,011 (287)

DNA methylation signatures associated with early-onset schizophrenia in Chinese patients. [PDF]

open access: yesTransl Psychiatry
Zhan N   +8 more
europepmc   +1 more source

Post‐Translational Regulation of CD8+ T Cell Fate and Dysfunction in Tumor Immunity

open access: yesAdvanced Science, EarlyView.
This review delineates how post‐translational modifications (PTMs) function as a central regulatory interface governing CD8+ T cell activation, differentiation, persistence, and exhaustion in antitumor immunity. By integrating antigenic, metabolic, and microenvironmental cues, diverse PTM programs coordinate transcriptional and chromatin states that ...
Zihao Zhou   +8 more
wiley   +1 more source

Programmable RNA N6,2´‐O‐Dimethyladenosine Editing

open access: yesAdvanced Science, EarlyView.
ABSTRACT N6,2’‐O‐dimethyladenosine (m6Am) is a prevalent RNA modification located at the first transcribed nucleotide adjacent to the 5′ cap of mRNAs, where it has been implicated in gene regulation. However, the lack of methods for precise, transcript‐specific manipulation of m6Am has limited its functional dissection.
Yang Li   +9 more
wiley   +1 more source

DNA methylation analysis of the epigenome in oral squamous cell carcinoma. [PDF]

open access: yesHum Genomics
Ma J   +7 more
europepmc   +1 more source

Grape Seed Polyphenols Enhance Antioxidant Activity and Prolong the Lifespan of Caenorhabditis elegans Through SKN‐1/Nrf2 Pathway

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
GSP extends C. elegans lifespan, enhances stress resistance and reproduction, boosts antioxidant defenses (↑SOD/CAT/GSH‐Px, ↓ROS), remodels glycolysis/TCA/one‐carbon metabolism dose‐dependently, and activates SKN‐1/Nrf2 and H3K4 methylation—linking redox control to epigenetic modulation.
Boya Ouyang   +7 more
wiley   +1 more source

DNA methylation

open access: yes, 2013
Marsha Reyngold, Timothy A. Chan
  +4 more sources

Supplementary Tables 1 from A Pre-Leukemic DNA Methylation Signature in Healthy Individuals at Higher Risk for Developing Myeloid Malignancy

open access: gold
Zhentang Lao   +15 more
openalex   +1 more source

Polymerase Chain Reaction. Perturbation Theory and Machine Learning Artificial Intelligence‐Experimental Microbiome Analysis: Applications to Ancient DNA and Tree Soil Metagenomics Cases of Study

open access: yesAdvanced Intelligent Systems, EarlyView.
The polymerase chain reaction (PCR).Perturbation Theory and Machine Learning framework integrates perturbation theory and machine learning to classify genetic sequences, distinguishing ancient DNA from modern controls and predicting tree health from soil metagenomic data.
Jose L. Rodriguez   +19 more
wiley   +1 more source

Non-disruptive in vitro monitoring of cellular states with cell-free DNA methylation. [PDF]

open access: yesGenome Biol
Hess A   +5 more
europepmc   +1 more source

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