Results 221 to 230 of about 2,768,548 (336)

The impact of environmental exposures on DNA methylation in the EXPANSE project. [PDF]

EBioMedicine
Vogli M, Jeong A, Yu Z, Vonk JM, Ibi D, Kronberg J, Gregor P, Maier L, Leskien M, Cirach M, Dadvand P, Mikeš O, Gruzieva O, Gehring U, Wolf K, Waldenberger M, Imboden M, Čupr P, de Hoogh K, Koppelman GH, Melén E, Pickford R, Thiering E, Standl M, Estonian Biobank Research Team, Klánová J, Vlaanderen J, Vermeulen R, Probst-Hensch N, Peters A, EXPANSE Project.   +30 more
europepmc   +1 more source

Features of the Arabidopsis recombination landscape resulting from the combined loss of sequence variation and DNA methylation [PDF]

, 2012
Maria Colomé‐Tatché, Sandra Cortijo, René Wardenaar, Lionel Morgado, Benoît Lahouze, Alexis Sarazin, Mathilde Etcheverry, Antoine Martin, Suhua Feng, Evelyne Duvernois‐Berthet, Karine Labadie, Patrick Wincker, Steven E. Jacobsen, Ritsert C. Jansen, Vincent Colot, Frank Johannes   +15 more
openalex   +1 more source

Effectiveness of Multivitamins vs Folic Acid on Prevention of Neural Tube Defects in Mouse Genetic Models and Human Organoids

Advanced Science, EarlyView.
Folic acid (FA) and multivitamins/minerals (MVM) are recommended for the prevention of neural tube defects (NTDs). Using a novel human neural tube‐like organoid system and mouse models, the study compares the effectiveness of two supplements on NTDs and cellular behaviors.
Huili Li, Jing Zhang, Lori Bulwith, Lee Niswander   +3 more
wiley   +1 more source

DNA methylation variability in pediatric aplastic anaemia contributes to T-cell differentiation. [PDF]

Clin Transl Med
Lai J, Chen F, Miao Y, Zhang M, Zhu H, Liang H, Yang L, Zhang Y, Tang D, Luo C, Luo C, Li Y, Wang X, Liu Y, Chen J, Qin X, Wang X.   +16 more
europepmc   +1 more source

Low YTHDC1 Expression Upregulates FSCN1 to Promote Nuclear F‐Actin Formation and Facilitate Double‐strand DNA Breaks Repair in TMZ‐Resistant Glioblastoma

Advanced Science, EarlyView.
This study revealed that low expression of YTHDC1 in TMZ‐resistant GBM cells leads to increased FSCN1 expression, which is suppressed by m6A modification. FSCN1 activates the CDC42/N‐WASP/Arp2/3 axis in the cell nucleus by recruiting the guanine nucleotide exchange factor (GEF) family member FGD1, thereby promoting F‐actin polymerization in the nucleus.
Minglong Yang, Wanxiang Niu, Yuanfei Wang, Peng Chen, Maolin Mu, Xiaoming Zhang, Ben Xu, Shanshan Hu, Chaoshi Niu, Pengfei Wu   +9 more
wiley   +1 more source

DNA Methylation in Lung Cancer: Predictive Biomarkers for Effective Immunotherapy. [PDF]

Int J Gen Med
Kumari K, Kumar V, Verma C, Hsu PC, Singh A.   +4 more
europepmc   +1 more source

Genome-wide DNA methylation profiling of leukocytes identifies CpG methylation signatures of aggressive prostate cancer.

, 2021
Yuyan Han, Mutian Zhang, Junfeng Xu, Jia Li, Yifan Xu, Timothy C. Thompson, Christopher J. Logothetis, Deqiang Sun, Jian Gu   +8 more
openalex   +1 more source

The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal Cancer

Advanced Science, EarlyView.
In wild‐type intestinal epithelial cells, KDM6B demethylates SLC10A2 to promote its expression, after which SLC10A2 suppresses ERK phosphorylation, inhibiting AP‐1 (Fos/Jun) transcription and chemokine production. In KDM6B‐deficient intestinal epithelial cells, SLC10A2 methylation increases, and its expression decreases.
Zhibo Hu, Jing Xun, Bin Liu, Xiaolin Jiang, Yingdi Han, Huichao Yang, Qi Gao, Ruifang Gao, Aimin Zhang, Xueliang Wu, Dapeng Zhang, Dihua Li, Tian Li, Shimin Yang, Ximo Wang, Xiangyang Yu, Qi Zhang   +16 more
wiley   +1 more source

Recent progress on DNA methylation in psoriasis. [PDF]

Front Genet
Lin Z, Wu X, Hong X, Luo D, Li H, Ma F, Huang C, Yu B, Gao J, Shen C.   +9 more
europepmc   +1 more source

Non-linear patterns in age-related DNA methylation may reflect CD4⁺ T cell differentiation [PDF]

, 2017
Nicholas D. Johnson, Howard W. Wiener, Alicia K. Smith, Shota Nishitani, Devin Absher, Donna K. Arnett, Stella Aslibekyan, Karen N. Conneely   +7 more
openalex   +1 more source