Results 261 to 270 of about 2,768,548 (336)

Performance evaluation of the DNA methylation biomarker SHOX2 for the aid in diagnosis of lung cancer based on the analysis of bronchial aspirates

, 2011
Dimo Dietrich
openalex   +2 more sources

Succinate Accumulation Links Mitochondrial MnSOD Depletion to Aberrant Nuclear DNA Methylation and Altered Cell Fate

, 2020
Kimberly Cramer-Morales, Collin D. Heer, Kranti A. Mapuskar, Frederick E. Domann   +3 more
openalex   +1 more source

Development of Dimethylsulfonium Probes for Broad Profiling of Methyllysine Reader Proteins

Advanced Science, EarlyView.
Development of oligoglycine‐based dimethylsulfonium probes for unbiased crosslinking to methyllysine readers. The general probe facilitates profiling of site‐specific methyllysine readers, evaluation of selectivity and activity of reader inhibitors, and global profiling of methyllysine readers.
Jinyu Yang, Yihang Xiao, Yingxiao Gao, Mingxuan Wu   +3 more
wiley   +1 more source

Exploring DNA methylation profiles in blood samples of canine gastrointestinal lymphoma. [PDF]

PLoS One
Nakamura M, Matsumoto Y, Nagata M, Yasuda K, Yonekawa K, Muramatsu S, Goshima A, Nakaki R, Yokoyama N, Nakashima K, Okumura M, Yamazaki J.   +11 more
europepmc   +1 more source

Structure‐Guided Engineering of a Promiscuous O‐Methyltransferase for a SAM Regeneration Biocatalysis Platform of Methylated Pharmaceuticals

Advanced Science, EarlyView.
A substrate promiscuous and regioselective O‐methyltransferase, SmOMT, is functionally and structurally characterized. A double mutant, SmOMTE152A/I306A, exhibited enhanced catalytic activity. By coupling this mutant with a mutant halide methyltransferase, AtHMTV140T, for SAM regeneration, a superior artificial fusion enzyme, AtHMTV140T‐L95‐SmOMTE152A ...
Xiran Xiong, Jun Song, Shihan Li, Lu Jin, Qi He, Baohui Zhang, Yan Cao, Shanyong Yi, Yanfang Yang, Xiang Li, Juan Li, Wei Huang   +11 more
wiley   +1 more source

Using DNA methylation to detect brain metastases before they spread. [PDF]

Ann Med Surg (Lond)
Ali MR, Panjwani R, Osman Abufatima I.
europepmc   +1 more source

Effectiveness of fecal DNA syndecan-2 methylation testing for detection of colorectal cancer in a high-risk Chinese population

Wenfeng Luo, Yuting Jiao, Xiaoling Lin, Ying Zhao, Shengbo Wang, Jian Shen, Jie Deng, Yufeng Ye, Zeping Han, Fangmei Xie, Jinhua He, Yu Wan   +11 more
openalex   +1 more source

Multi‐Tissue Genetic Regulation of RNA Editing in Pigs

Advanced Science, EarlyView.
This study presents the first multi‐tissue map of RNA editing and its genetic regulation in pigs. By integrating RNA editing profiles, edQTL mapping, GWAS, and cross‐species comparisons, this work establishes RNA editing as a distinct regulatory layer linking genetic variation to complex traits, highlighting its functional and evolutionary significance.
Xiangchun Pan, Wentao Gong, Xiaodian Cai, Jinyan Teng, Jiali Cai, Haonan Zeng, Wondossen Ayalew, Qingpeng Shen, Zhanming Zhong, Yifei Wang, Wenjing Zhang, Yuhan Tian, Dantong Xu, Yahui Gao, Hongwei Yin, Yuebo Zhang, Jiahui Hou, Tianru Zhou, Jiaqi Li, Lingzhao Fang, Xiaolong Yuan, Zhe Zhang   +21 more
wiley   +1 more source

Mucosal DNA methylation reveals immune-related methylation profile and correlates with crohn's disease status. [PDF]

Sci Rep
Zhang T, Lin Q, Xu WY, He Q, Gong C, Wang L, Wang Z, Zhong J.   +7 more
europepmc   +1 more source