Results 261 to 270 of about 2,686,549 (398)

DNA Methylation and Expression of the Genes Coding for Lactate Dehydrogenases A and C during Rodent Spermatogenesis1 [PDF]

, 1991
Acacia A. Alcivar, Jacquetta M. Trasler, Laura E. Hake, Kourosh Salehi‐Ashtiani, Erwin Goldberg, Norman B. Hecht   +5 more
openalex   +1 more source

Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance

Advanced Science, EarlyView.
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai, Kefei Wu, Qi Lin, Zhenzhen Cao, Yankun Jia, Ping Zhu   +5 more
wiley   +1 more source

Maternal asthma and newborn DNA methylation. [PDF]

Clin Epigenetics
Pedersen CT, Hoang TT, Jin J, Starnawska A, Granell R, Elliott HR, Huels A, Zar HJ, Stein DJ, Zhang Y, Dekker HTD, Duijts L, Felix JF, Sangüesa J, Bustamante M, Casas M, Vrijheid M, Kadalayil L, Rezwan FI, Arshad H, Holloway JW, Röder S, Zenclussen AC, Herberth G, Staunstrup NH, Horsdal HT, Mill J, Hannon E, iPSYCH-MINERvA Group, Annesi-Maesano I, Pesce G, Baïz N, Heude B, Hosseinian-Mohazzab S, Breton CV, Harlid S, Harbs J, Domellof M, West C, Yeung E, Zeng X, Nystad W, Håberg SE, Magnus MC, Schendel D, London SJ, Bønnelykke K.   +46 more
europepmc   +1 more source

The TET3/GATA6 Axis Drives Lipid Metabolism and Therapeutic Vulnerabilities in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
The DNA demethylase TET3 drives lipid metabolic reprogramming in pancreatic ductal adenocarcinoma via a non‐catalytic mechanism. TET3 recruits histone deacetylases to repress GATA6, sustaining lipogenic enzyme expression and ferroptosis resistance.
Shuai Liu, Shaobo Kang, Na Lin, Wenqi Zhang, Shiwen Wang, Yuqing Ren, Xiaofan Ding, Jianxiu Yu, Ruiyu Xie   +8 more
wiley   +1 more source

DNA methylation protects cancer cells against senescence. [PDF]

Nat Commun
Chen X, Yamaguchi K, Rodgers B, Goehrig D, Vindrieux D, Lahaye X, Nolot M, Ferry L, Lanciano S, Martin N, Dubus P, Miura F, Ito T, Cristofari G, Manel N, Kanemaki MT, Bernard D, Defossez PA.   +17 more
europepmc   +1 more source

Carcinogenic Nickel Silences Gene Expression by Chromatin Condensation and DNA Methylation: a New Model for Epigenetic Carcinogens [PDF]

, 1995
Y.-W. Lee, Catherine B. Klein, B. Kargačin, Konstantin Salnikow, Jun Kitahara, Karol Dowjat, Anatoly Zhitkovich, Nelwyn T. Christie, Max Costa   +8 more
openalex   +1 more source

Histone Demethylase UTX Suppresses Tumor Cell Proliferation by Regulating Stress Granules

Advanced Science, EarlyView.
These findings indicate that cytoplasmic UTX forms puncta and co‐localizes in stress granules (SGs) upon various stresses. UTX TPR‐domain‐dependently and demethylase‐activity‐independently destabilize SGs by binding G3BP1, the SG hub protein, to disrupt SG network, thus affects tumorigenesis.
Xikai Liu, Xinran Liu, Mei Xue, Yushuo Xiao, Yuchen Chen, Rong Qiu, Di Wu, Yihao Zhou, Jiao Wang, Yan Yuan, Linwei Yu, Tianyi Shi, Yangkai Li, Hua Su, Hong Chen, Yong Liu, Kun Huang, Ling Zheng   +17 more
wiley   +1 more source

DNA Methylation: A Key Regulator in Male and Female Reproductive Outcomes. [PDF]

Life (Basel)
Adetunji AO, Owusu H, Adewale EF, Adesina PA, Xedzro C, Saliu TP, Islam S, Zhu Z, Morenikeji OB.   +8 more
europepmc   +1 more source

A simple high-resolution procedure to study DNA methylation and in vivo DNA-protein interactions on a single-copy gene level in higher eukaryotes.

, 1989
H. P. Saluz, J P Jost
openalex   +1 more source

DNA methylation inhibits elongation but not initiation of transcription in Neurospora crassa [PDF]

, 1997
Michael R. Rountree, Eric U. Selker
openalex   +1 more source