Results 51 to 60 of about 2,729,754 (384)
Comprehensive profiling of zebrafish hepatic proximal promoter CpG island methylation and its modification during chemical carcinogenesis [PDF]
, 2011 Background\ud DNA methylation is an epigenetic mechanism associated with regulation of gene expression and it is modulated during chemical carcinogenesis.
Chipman, J Kevin +4 more
core +4 more sources
, 2023 DNA methylation, one of the most studied epigenetic modifications, refers to the addition of a methyl group to the fifth carbon of cytosine (C) catalyzed by DNA methyltransferases(Dnmts), forming 5-methylcytosine (5mC). DNA methylation predominantly occurs inCpGs but is also found in non-CpG contexts.
openaire +1 more source
Frontiers in Chemistry, 2023 DNA methylation plays an important physiological function in cells, and environmental changes result in fluctuations in DNA methylation levels. Metal ions have become both environmental and health concerns, as they have the potential to disrupt the ...
Shan Liu +4 more
doaj +1 more source
Decreased DNA methylation of a CpG site in the HBAP1 gene in plasma DNA from pregnant women. [PDF]
PLoS ONE, 2018 OBJECTIVE:The objective of this study is to identify potential CpG site(s) or DNA methylation pattern(s) in the pseudo α-globin 1 gene (HBAP1 gene), the gene which locates in α-thalassemia-1 deletion mutation, to differentiate plasma DNA between pregnant
Tanapat Pangeson +3 more
doaj +1 more source
Role of genetic and environmental factors in DNA methylation of lipid metabolism
Genes and Diseases, 2018 A number of recent studies revealed that DNA methylation plays a central role in the regulation of lipid metabolism. DNA methylation modifications are important regulators of transcriptional networks that do not affect the DNA sequence and can translate ...
Zhen He +4 more
doaj +1 more source
In utero tobacco smoke exposure, DNA methylation, and asthma in Latino children. [PDF]
, 2019 BackgroundMaternal smoking during pregnancy is a risk factor for chronic disease later in life and has been associated with variability of DNA methylation at specific cytosine-phosphate-guanine (CpG) loci.
Barker +47 more
core +1 more source
Parenting stress and DNA methylation among African Americans in the InterGEN Study
Journal of Clinical and Translational Science, 2017 IntroductionGeneral life stress has been associated with altered DNA methylation in individuals of African Ancestry, although the relationship between parenting stress and DNA methylation has not been described.
Michelle L. Wright +6 more
doaj +1 more source
Methylation of chromatin DNA [PDF]
Nucleic Acids Research, 1976 E. coli DNA methylase has been used to methylate chromatin DNA in vitro. At saturation only 50% of the chromatin DNA becomes methylated. The methylated regions of chromatin correspond to that fraction of the chromatin which is sensitive to staphylococcal nuclease.
Howard Cedar, Shoshana Bloch
openaire +2 more sources
Cell Reports, 2017 Summary: DNA methylation plays crucial roles in chromatin structure and gene expression. Aberrant DNA methylation patterns, including global hypomethylation and regional hypermethylation, are associated with cancer and implicated in oncogenic events. How
Nicolas Veland +8 more
doaj +1 more source
DNA methylation arrays as surrogate measures of cell mixture distribution
BMC Bioinformatics, 2012 There has been a long-standing need in biomedical research for a method that quantifies the normally mixed composition of leukocytes beyond what is possible by simple histological or flow cytometric assessments.
E. Houseman +7 more
semanticscholar +1 more source