Results 181 to 190 of about 151,241 (263)

DNA-methylation aging at single-cell level

Nature Aging, 2021
openaire   +2 more sources

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Interplay of education and DNA methylation age on cognitive impairment: insights from the Health and Retirement Study. [PDF]

Geroscience
Ware EB, Higgins Tejera C, Wang H, Harris S, Fisher JD, Bakulski KM.   +5 more
europepmc   +1 more source

Editorial: Computational methods for analysis of DNA methylation data, volume II

Frontiers in Bioinformatics
Pietro Di Lena, Christine Nardini, Matteo Pellegrini   +2 more
doaj   +1 more source

Newborn DNA methylation age differentiates long-term weight trajectories: the Boston Birth Cohort. [PDF]

BMC Med
Yaskolka Meir A, Wang G, Hong X, Hu FB, Wang X, Liang L.   +5 more
europepmc   +1 more source

Symposium Review: Wild Animal Welfare is in Our Backyards

The Bulletin of the Ecological Society of America, EarlyView.
Bonnie Fairbanks Flint, David R. Daversa, M. Camille Hopkins, Jessica X. Wright‐Lichter   +3 more
wiley   +1 more source

Decoding epilepsy's molecular blueprint: Machine learning unravels transcriptomic subtypes and regulatory networks

Epilepsia, EarlyView.
Abstract Objective Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy. The molecular heterogeneity underlying DRE remains poorly defined, largely due to limited access to resected brain tissue and substantial genetic diversity.
Yanping Weng, Yu Ma, Wanwan Hou, Haibo Li, Yuanfeng Zhou, Rui Zhao, Hao Li, Lian Chen, Yangyang Ma, Li Jin, Yi Wang, Yu An   +11 more
wiley   +1 more source

Associations of childhood, adolescence, and midlife cognitive function with DNA methylation age acceleration in midlife. [PDF]

Aging (Albany NY)
Chen J, Moubadder L, Clausing ES, Kezios KL, Conneely KN, Hüls A, Baccarelli A, Factor-Litvak P, Cirrillo P, Shelton RC, Link BG, Suglia SF.   +11 more
europepmc   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola, Marica Rubino, Antonella Riva, Pasquale Striano   +3 more
wiley   +1 more source