Results 111 to 120 of about 297,565 (330)

2022-RA-1499-ESGO Differential response of in-vitro mismatch repair-deficient hypermethylated endometrioid endometrial cancer models to DNA-hypomethylating agents [PDF]

, 2022
Louis Y. El Khoury, Wan Hsin Lin, James B. Smadbeck, Dorsay Sadeghian, John C. Cheville, Faye R. Harris, Lindsey Kinsella, Marina Walther Antonio, Giuseppe Cucinella, Gabriella Schivardi, Alexa McCune, Giannoula Karagouga, Aaron S. Mansfield, Andrea Mariani, George Vasmatzis, Panos Z. Anastasiadis, S. John Weroha, Alyssa Larish   +17 more
openalex   +1 more source

Rustless translation [PDF]

, 2012
ATP binding cassette proteins are a large and diverse family of molecular machines and include transmembrane transporter, chromosome maintenance and DNA repair proteins, and translation factors.
Karl-Peter Hopfner, Roy
core   +1 more source

Nanostructured Protein Surfaces Inspired by Spider Silk

Advanced Materials, EarlyView.
Harnessing recombinant spider silk technology, bioengineered spidroin variants enable the creation of functionalized nanostructured coatings with tunable affinity for specific targets, supporting a broad range of applications ‐ from antifouling surfaces and targeted drug delivery to advanced cell therapies and precision bio‐patterning via lithography ...
Martin Humenik, Thomas Scheibel
wiley   +1 more source

MMR deficiency is frequent in colorectal carcinomas with diffuse SLFN11 immunostaining: clinicopathologic and molecular study of 31 cases identified among 3,300 tumors

The Journal of Pathology: Clinical Research
Schlafen 11 (SLFN11), a regulator of cell fate following DNA injury, sensitizes tumor cells to DNA‐damaging agents. Patients with SLFN11‐positive tumors may benefit from DNA‐damaging chemotherapies.
Maciej Kaczorowski, Małgorzata Chłopek, Ondřej Daum, Kris Ylaya, Tomáš Vaněček, Magdalena Szczepaniak, Karol Krawczyk, Artur Kowalik, Michal Michal, Jerzy Lasota, Markku Miettinen   +10 more
doaj   +1 more source

Mlh1-Mlh3, a Meiotic Crossover and DNA Mismatch Repair Factor, Is a Msh2-Msh3-stimulated Endonuclease*

Journal of Biological Chemistry, 2014
Background: Meiotic crossing over requires resolution of Holliday junctions through actions of the DNA mismatch repair factor Mlh1-Mlh3. Results: Mlh1-Mlh3 is a metal-dependent, Msh2-Msh3-stimulated endonuclease.
M. Rogacheva, Carol M. Manhart, Cheng Chen, A. Guarné, J. Surtees, E. Alani   +5 more
semanticscholar   +1 more source

Biological and Biologically Inspired Functional Nanostructures: Insights into Structural, Optical, Thermal, and Sensing Applications

Advanced Materials, EarlyView.
Biological and biologically‐inspired functional nanostructures with structural, thermal, optical, and sensing applications are reviewed. The role of nanoscale features in biological materials on performance is described, and their blueprints are used for bio‐inspired nanomaterials, synthesized using advanced techniques (i.e., photolithography, bio ...
Chao Hsuan (Joseph) Sung, Taige Hao, Herry Fang, Andrew Tran Nguyen, Valentina Perricone, Haitao Yu, Wei Huang, Ezra Sarmiento, Adrian Francisco Duran Ornelas, Derek Lublin, Ric Wehling, Sanaz Farajollahi, Atsushi Arakaki, Dhriti Nepal, Nathan Patrick Lord, David Kisailus   +15 more
wiley   +1 more source

Mismatch repair genes in Lynch syndrome: a review

São Paulo Medical Journal
Lynch syndrome represents 1-7% of all cases of colorectal cancer and is an autosomal-dominant inherited cancer predisposition syndrome caused by germline mutations in deoxyribonucleic acid (DNA) mismatch repair genes.
Felipe Cavalcanti Carneiro da Silva, Mev Dominguez Valentin, Fábio de Oliveira Ferreira, Dirce Maria Carraro, Benedito Mauro Rossi   +4 more
doaj   +1 more source

Advances of DNA Damage Repair and Cisplatin Resistance Mechanisms in Lung Cancer

Chinese Journal of Lung Cancer, 2011
Lung cancer is the most common cause of death from cancer worldwide per year. Platinum-based combination chemotherapy is a main treatment of lung cancer. Cisplatin is adopted widely and used effectively in the first-line chemotherapy.
Chunlan TANG, Heping YANG, Xiangdong ZHOU   +2 more
doaj   +1 more source

Regulation of the DNA replication fork: a way to fight genomic instability [PDF]

, 2018
DNA replication is a complex mechanism that functions due to the coordinated interplay of many factors. In the last few years, numerous studies have suggested that DNA replication factors are closely implicated in several DNA transaction events that ...
Hübscher, Ulrich, Toueille, Magali
core  

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source