Results 11 to 20 of about 743,722 (313)
Modification of Subtelomeric DNA [PDF]
Molecular and Cellular Biology, 2004 There is a discrepancy in telomere length as measured by signal intensity of telomere restriction fragments on gels and fluorescence in situ hybridization analysis. This difference has been ascribed to the X-region, a segment of subtelomeric DNA that is resistant to being cut by restriction enzymes. To explore the nature of this region, we analyzed the
Susanne, Steinert +2 more
openaire +2 more sources
DNA N6-Methyladenine Modification in Eukaryotic Genome
Frontiers in Genetics, 2022 DNA methylation is treated as an important epigenetic mark in various biological activities. In the past, a large number of articles focused on 5 mC while lacking attention to N6-methyladenine (6 mA).
Hao Li +14 more
doaj +1 more source
Genetic Modification of Sodalis Species by DNA Transduction
mSphere, 2021 A large number of economically important insects maintain intimate associations with maternally inherited endosymbiotic bacteria. Due to the inherent nature of these associations, insect endosymbionts cannot be usually isolated in pure culture or ...
Chelsea M. Keller +4 more
doaj +1 more source
Catalytic DNA Nanocranes for Controlled Protein Modification in Cell Lysate
, 2023 This paper describes the development and performance of catalytic crane-like DNA nanostructures for the controlled modification of wild-type proteins.
Jordi, Keijzer, Bauke, Albada
core +1 more source
Alleviation of C⋅C Mismatches in DNA by the Escherichia coli Fpg Protein
Frontiers in Microbiology, 2021 DNA polymerase III mis-insertion may, where not corrected by its 3′→ 5′ exonuclease or the mismatch repair (MMR) function, result in all possible non-cognate base pairs in DNA generating base substitutions.
Almaz Nigatu Tesfahun +10 more
doaj +1 more source
Allele-Specific PCR for PIK3CA Mutation Detection Using Phosphoryl Guanidine Modified Primers
Diagnostics, 2023 Phosphoryl guanidine (PG) is the novel uncharged modification of internucleotide phosphates of oligonucleotides. Incorporating PG modification into PCR primers leads to increased discrimination between wild-type and mutated DNA, providing extraordinary ...
Alexey S. Chubarov +5 more
doaj +1 more source
Oxidative coupling for facile, stable carbon modification with DNA and proteins
, 2022 Modification of electrodes with biomolecules is an essential first step for the development of biosensors. Conventionally, gold electrodes are used because of their ease of modification with thiolated biomolecules.
Amruta, Karbelkar +4 more
core +1 more source
Frontiers in Microbiology, 2023 DNA methylation events mediated by orphan methyltransferases modulate various cellular processes like replication, repair and transcription. Bacteria and archaea also harbor DNA methyltransferases that are part of restriction-modification systems, which ...
Pallavi Gulati +3 more
doaj +1 more source
DNA methylation assessed by SMRT sequencing is linked to mutations in Neisseria meningitidis isolates [PDF]
, 2015 The Gram-negative bacterium Neisseria meningitidis features extensive genetic variability. To present, proposed virulence genotypes are also detected in isolates from asymptomatic carriers, indicating more complex mechanisms underlying variable ...
Gerd Pluschke +26 more
core +1 more source
BMC Genomics, 2019 Background DNA methylation is an important epigenetic modification. Recently the developed single-molecule real-time (SMRT) sequencing technology provided an efficient way to detect DNA N6-methyladenine (6mA) modification that played an important role in
Mei-Wei Luan +5 more
doaj +1 more source