Results 11 to 20 of about 3,282,036 (289)

Polymerase Mu Is a DNA-Directed DNA/RNA Polymerase [PDF]

open access: yesMolecular and Cellular Biology, 2003
DNA polymerases are defined as such because they use deoxynucleotides instead of ribonucleotides with high specificity. We show here that polymerase mu (pol μ), implicated in the nonhomologous end-joining pathway for repair of DNA double-strand breaks, incorporates both ribonucleotides and deoxynucleotides in a template-directed manner.
Stephanie A. Nick McElhinny   +1 more
openaire   +3 more sources

Identifikasi berbasis karakter molekuler Nucleopolyhedrovirus pada larva Helicoverpa armigera Hubner (Lepidoptera: Noctuidae) asal Bogor, Jawa Barat

open access: yesJurnal Entomologi Indonesia, 2022
Identification based on molecular character of Nucleopolyhedrovirusin Helicoverpa armigera Hubner (Lepidoptera: Noctuidae) larvae from Bogor, West Java.
R. Yayi Munara Kusumah   +2 more
doaj   +1 more source

Accessibility of DNA in Chromatin to DNA Polymerase and RNA Polymerase [PDF]

open access: yesProceedings of the National Academy of Sciences, 1973
The accessibility of DNA in chromatin to both exogenous DNA polymerase and RNA polymerase is slight when compared to isolated DNA. DNA in extracted chromatin is somewhat more accessible to these enzymes than is DNA in the chromatin of isolated nuclei; and the DNA template of chromatin is more accessible to DNA polymerase than to RNA polymerase.
Bert Silverman, Alfred E. Mirsky
openaire   +3 more sources

Replicative DNA Polymerases [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2013
In 1959, Arthur Kornberg was awarded the Nobel Prize for his work on the principles by which DNA is duplicated by DNA polymerases. Since then, it has been confirmed in all branches of life that replicative DNA polymerases require a single-stranded template to build a complementary strand, but they cannot start a new DNA strand de novo.
Johansson, Erik, Dixon, Nicholas
openaire   +4 more sources

The human CTF4-orthologue AND-1 interacts with DNA polymerase α/primase via its unique C-terminal HMG box [PDF]

open access: yesOpen Biology, 2017
A dynamic multi-protein assembly known as the replisome is responsible for DNA synthesis in eukaryotic cells. In yeast, the hub protein Ctf4 bridges DNA helicase and DNA polymerase and recruits factors with roles in metabolic processes coupled to DNA ...
Mairi L. Kilkenny   +5 more
doaj   +1 more source

Cloning of DNA Polymerase I Geobacillus thermoleovorans SGAir0734 from a Batu Kuwung Hot Spring in Escherichia coli

open access: yesInternational Journal of Technology, 2020
Access to biological engineering has become a critical point of modern science development through polymerase chain reaction (PCR). One of the main components in this process is DNA polymerase, which copies the main template DNA.
Kenny Lischer   +5 more
doaj   +1 more source

The DNA polymerases of Drosophila melanogaster

open access: yesFly, 2020
DNA synthesis during replication or repair is a fundamental cellular process that is catalyzed by a set of evolutionary conserved polymerases.
Steven J. Marygold   +9 more
doaj   +1 more source

Polymerization Domain Translated from 0.9 kb Gene Fragment of DNA Polymerase I from a Thermo-Halophilic PLS A Strain

open access: yesJurnal Kimia Sains dan Aplikasi, 2020
The search for novel DNA Polymerases I, with higher fidelity and better polymerization rate, is essential to improve the Polymerase Chain Reaction method.
Teuku Mohamad Iqbalsyah   +3 more
doaj   +1 more source

DNA Helicase–Polymerase Coupling in Bacteriophage DNA Replication

open access: yesViruses, 2021
Bacteriophages have long been model systems to study the molecular mechanisms of DNA replication. During DNA replication, a DNA helicase and a DNA polymerase cooperatively unwind the parental DNA.
Chen-Yu Lo, Yang Gao
doaj   +1 more source

The Loop of the TPR1 Subdomain of Phi29 DNA Polymerase Plays a Pivotal Role in Primer-Terminus Stabilization at the Polymerization Active Site

open access: yesBiomolecules, 2019
Bacteriophage Phi29 DNA polymerase belongs to the protein-primed subgroup of family B DNA polymerases that use a terminal protein (TP) as a primer to initiate genome replication. The resolution of the crystallographic structure showed that it consists of
Alicia del Prado   +4 more
doaj   +1 more source

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