Results 231 to 240 of about 3,282,036 (289)

Structural insights into a DNA polymerase reading the xeno nucleic acid HNA. [PDF]

Nucleic Acids Res
Gutfreund C, Betz K, Abramov M, Coosemans F, Holliger P, Herdewijn P, Marx A.   +6 more
europepmc   +1 more source

Hepatitis E Virus ORF1 Polyprotein Harbors a Pocket‐Like Cavity That Is Vital for Virus Replication and Represents a Novel Antiviral Target

Advanced Science, EarlyView.
Within the hepatitis E virus (HEV) ORF1 polyprotein, the X domain interacts with viral RNA‐dependent RNA polymerase (RdRp), forming a functional “pocket‐like” cavity (PC) that is crucial for viral replication. Structure‐based screening, surface plasmon resonance (SPR) assays, and HEV model validation collectively identify saikosaponin D and ...
Xiaohui Ding, Dou Zeng, Dan Liu, Yingying Bian, Bin Li, Zheng Li, Qiudi Li, Shiquan Liang, Yunlong Si, Qili Yao, Yibo Ding, Jiahui Zhu, Xiangyang Li, Kuiyang Zheng, Hongbo Guo, Wenshi Wang   +15 more
wiley   +1 more source

DNA polymerase α/primase extraction from chromatin by VCP/p97 restricts ATR activation during unperturbed DNA replication. [PDF]

Nat Commun
Rodríguez-Acebes S, Martín-Rufo R, Gómez-Moya A, Churcher SB, Fernández-Llorente A, de la Vega-Barranco G, Perona A, Oroz P, Martín-Doncel E, Toledo LI, Méndez J, Lecona E.   +11 more
europepmc   +1 more source

A conserved thumb domain insertion in DNA polymerase epsilon supports processive DNA synthesis. [PDF]

Nucleic Acids Res
Ahmad S, Zhang S, Meng X.
europepmc   +1 more source

DNA-Binding Activities of KSHV DNA Polymerase Processivity Factor (PF-8) Complexes. [PDF]

Viruses
Travis JK, Martin M, Costantini LM.
europepmc   +1 more source

Replicative DNA polymerase epsilon and delta holoenzymes show wide-ranging inhibition at G-quadruplexes in the human genome. [PDF]

Nucleic Acids Res
Hile SE, Weissensteiner MH, Pytko KG, Dahl J, Kejnovsky E, Kejnovská I, Hedglin M, Georgakopoulos-Soares I, Makova KD, Eckert KA.   +9 more
europepmc   +1 more source

Random amplified polymorphic DNA polymerase chain reaction was used to analyze the genotype and diversity of <i>Pseudomonas aeruginosa</i> isolated from salmon trout farms with hemorrhagic septicemia. [PDF]

Open Vet J
Taha ZM.
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

DNA polymerase ε.

Sub-cellular biochemistry, 2012
DNA polymerase ε (Pol ε) is one of three replicative DNA polymerases in eukaryotic cells. Pol ε is a multi-subunit DNA polymerase with many functions. For example, recent studies in yeast have suggested that Pol ε is essential during the initiation of DNA replication and also participates during leading strand synthesis.
Matthew Hogg, E. Johansson
semanticscholar   +4 more sources

Eukaryotic DNA Polymerases

Annual Review of Biochemistry, 2002
▪ Abstract  Any living cell is faced with the fundamental task of keeping the genome intact in order to develop in an organized manner, to function in a complex environment, to divide at the right time, and to die when it is appropriate. To achieve this goal, an efficient machinery is required to maintain the genetic information encoded in DNA during ...
Hubscher U, Maga G, Spadari S
openaire   +5 more sources