Results 231 to 240 of about 945,929 (245)

Bisphenol B Exposure Induces Miscarriage by Suppressing Migration/Invasion and Migrasome Formation

Advanced Science, EarlyView.
BPB (Bisphenol B) exposure up‐regulates ER (estrogen receptor) levels, enhances its interactions with the lnc‐HZ04 promoter region, and thus promotes ER‐mediated lnc‐HZ04 transcription. Subsequently, lnc‐HZ04 suppresses TCF4 (transcription factor 4)‐mediated PKCA (protein kinase C alpha) transcription and subsequently suppresses migration/invasion and ...
Wenxin Huang, Manli Wang, Yi Sun, Xiaoping Yue, Xun Li, Yanbing Lin, Geng Guo, Depeng Zhao, Qigang Fan, Xiaoling Ma, Zhihong Zhang, Shuaishuai Xing, Xiaoting Shen, Huidong Zhang   +13 more
wiley   +1 more source

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes. [PDF]

J Vis Exp
Kusi-Appauh N, Mueller SH, Ralph SF, Yurieva O, O'Donnell ME, Lewis JS, Spenkelink LM.   +6 more
europepmc   +1 more source

A Unique Chimeric RNA: ERCC1‐iASPP Drives Benzo[a]pyrene‐Induced Lung Carcinogenesis via Dual Coding and Non‐Coding Mechanisms

Advanced Science, EarlyView.
The chimeric RNA ERCC1‐iASPP possesses dual coding and non‐coding functions, synergistically accelerating the process of cellular malignant transformation. Abstract Genetic variation at 19q13.3 critically modulates chemical carcinogen‐induced lung carcinogenesis, particularly in mediating the activity of benzo[a]pyrene (B[a]P), a major polycyclic ...
Mingming Shan, Mingyang Xiao, Liang Zhang, Shen Wang, Jiahang Wu, Kang Cao, Yujin Li, Guopei Zhang, Junwei Xie, Xiaobo Lu   +9 more
wiley   +1 more source

(±)-2-Cyclohexyl-5-methoxy-2H-chromene, a Synthetic 5-Methoxyflavone Derivative, Is a Selective DNA Polymerase-β Inhibitor with Neuroprotective Activity against β-Amyloid Toxicity. [PDF]

ACS Chem Neurosci
Guccione S, Merlo S, Tagliapietra S, Pappalardo M, Binello A, Barge A, Basile L, Sortino MA, Cravotto G, Copani A.   +9 more
europepmc   +1 more source

Epstein‐Barr Virus Expressed Long Non‐Coding RNA (lncBARTs) Regulate EBV Latent Genome Replication

Advanced Science, EarlyView.
EBV produces abundant level of lncBARTs, which are essential for maintaining viral genome replication in EBV‐associated cancers. LncBARTs interact with a complex comprising BRD4, CTCF and viral protein EBNA1 at EBV oriP region. This interaction tethers oriP to host chromosomes, facilitating EBV episome replication.
Jiayan Liu, Dittman Lai‐Shun Chung, Larry Ka‐Yue Chow, Shuo Han, Wenkai Yi, Conor J. Cremin, Yingyin Liao, Pui Wang, Bobo Wing‐Yee Mok, Mingfang Ji, Jian Yan, Wei Dai, Honglin Chen   +12 more
wiley   +1 more source

Identification of EppR, a Second Repressor of Error-Prone DNA Polymerase Genes in Acinetobacter baumannii. [PDF]

Mol Microbiol
Nguyen B, Ching C, MacGuire A, Casula P, Newman C, Finley F, Godoy VG.   +6 more
europepmc   +1 more source

Correction to 'Pathogen-encoded Rum DNA polymerase drives rapid bacterial drug resistance'. [PDF]

Nucleic Acids Res
europepmc   +1 more source

TRIP12's role in the governance of DNA polymerase β involvement in DNA damage response and repair. [PDF]

Nucleic Acids Res
Inanc B, Fang Q, Roos WP, Andrews JF, Zeng X, Clark J, Li J, Dey NB, Ibrahim M, Sykora P, Yu Z, Pearson CR, Braganza A, Verheij M, Jonkers J, Yates NA, Vens C, Sobol RW.   +17 more
europepmc   +1 more source

DNA polymerase epsilon-mutant colorectal cancers: Insights into non-exonuclease domain mutation variants, microsatellite instability status, and co-mutation profiles. [PDF]

World J Gastroenterol
Taskiran I, Orenay-Boyacioglu S, Boyacioglu O, Erdogdu IH, Culhaci N, Meteoglu I.   +5 more
europepmc   +1 more source

A human high-fidelity DNA polymerase holoenzyme has a wide range of lesion bypass activities. [PDF]

Nucleic Acids Res
Dannenberg RL, Cardina JA, Washington H, Gao S, Greenberg MM, Hedglin M.   +5 more
europepmc   +1 more source