Results 121 to 130 of about 1,066,757 (310)

Trypanosome diversity in wildlife species from the Serengeti and Luangwa Valley ecosystems [PDF]

open access: yes, 2012
<p>Background: The importance of wildlife as reservoirs of African trypanosomes pathogenic to man and livestock is well recognised. While new species of trypanosomes and their variants have been identified in tsetse populations, our knowledge of ...
Richard Hoare   +47 more
core   +1 more source

SELEÇÃO DE MARCADORES ISSR PARA Schizolobium parahyba var. amazonicum (Huber ex. Ducke) Barneby

open access: yesRevista UniVap, 2017
O objetivo deste trabalho foi selecionar primers ISSR para serem utilizados em futuras análises de diversidade genética em população de S. amazonicum, conhecido popularmente como Paricá.
Adelson Lemes da Silva Júnior   +8 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Comparison of Two Multiplex PCR Systems for Meat Species Authentication

open access: yesJournal of Food Quality and Hazards Control, 2019
Background: Meat species adulteration has become a problem of concern. This study aimed to compare two previously published multiplex Polymerase Chain Reaction (PCR) methods for meat species authentication.
D. Al-taghlubee   +5 more
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Deep sequencing of plant and animal DNA contained within traditional Chinese medicines reveals legality issues and health safety concerns [PDF]

open access: yes, 2012
Traditional Chinese medicine (TCM) has been practiced for thousands of years, but only within the last few decades has its use become more widespread outside of Asia. Concerns continue to be raised about the efficacy, legality, and safety of many popular
Michael Bunce   +43 more
core   +2 more sources

Amplifying DNA with arbitrary oligonucleotide primers. [PDF]

open access: yesGenome Research, 1993
G e n e t i c molecular markers are DNA segments that behave as landmarks for genome analysis. These segments usually represent variant or polymorphic sites that can be identified using general strategies such as molecular hybridization or enzymatic amplification of DNA.
openaire   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Hematopoietic chimerism after allogeneic stem cell transplantation : a comparison of quantitative analysis by automated DNA sizing and fluorescent in situ hybridization [PDF]

open access: yes, 2005
Background: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is performed mainly in patients with high-risk or advanced hematologic malignancies and congenital or acquired aplastic anemias.
Wachowiak, Jacek   +13 more
core   +1 more source

PEMILIHAN PRIMER RAPD (RANDOM AMPLIFIED POLYMORPHIC DNA) PADA PCR (POLYMERASE CHAIN REACTION) TANAMAN KAMBOJA (Plumeria sp.)

open access: yesSimbiosis: Journal of Biological Sciences, 2016
There are many variation of Plumeria sp. that grown in Bali. The genetic identity of Plumeria sp. need to be analysed using molecular study for plant breeding purpose.
Vanesa Martida, Made Pharmawati
doaj  

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