Results 41 to 50 of about 391,854 (357)

EcoRV catalysis with a pre-bent substrate

open access: yesAIP Advances, 2015
Enzymes are deformable molecules which often adapt their conformation to the substrate’s geometry. In the case of restriction enzymes acting on DNA, the substrate (DNA) is deformable also.
Daniel S. Sanchez, Giovanni Zocchi
doaj   +1 more source

APOBECs and Herpesviruses

open access: yesViruses, 2021
The apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like (APOBEC) family of DNA cytosine deaminases provides a broad and overlapping defense against viral infections.
Adam Z. Cheng   +8 more
doaj   +1 more source

Machines on Genes: Enzymes that Make, Break and Move DNA and RNA [PDF]

open access: yes, 2010
As the vital information repositories of the cell, the nucleic acids DNA and RNA pose many challenges as enzyme substrates. To produce, maintain and repair DNA and RNA, and to extract the genetic information that they encode, a battery of remarkable ...
Bates   +13 more
core   +1 more source

REHUNT: a reliable and open source package for restriction enzyme hunting

open access: yesBMC Bioinformatics, 2018
Background Restriction enzymes are used frequently in biotechnology. However, manual mining of restriction enzymes is challenging. Furthermore, integrating available restriction enzymes into different bioinformatics systems is necessary for many ...
Yu-Huei Cheng   +2 more
doaj   +1 more source

2b-RAD genotyping for population genomic studies of Chagas disease vectors: Rhodnius ecuadoriensis in Ecuador [PDF]

open access: yes, 2017
Background: Rhodnius ecuadoriensis is the main triatomine vector of Chagas disease, American trypanosomiasis, in Southern Ecuador and Northern Peru.
Andersson, Björn   +10 more
core   +4 more sources

Cytosine-to-Uracil Deamination by SssI DNA Methyltransferase [PDF]

open access: yes, 2013
The prokaryotic DNA(cytosine-5)methyltransferase M.SssI shares the specificity of eukaryotic DNA methyltransferases (CG) and is an important model and experimental tool in the study of eukaryotic DNA methylation.
A Beletskii   +47 more
core   +8 more sources

A novel zinc-finger nuclease platform with a sequence-specific cleavage module [PDF]

open access: yes, 2011
Zinc-finger nucleases (ZFNs) typically consist of three to four zinc fingers (ZFs) and the non-specific DNA-cleavage domain of the restriction endonuclease FokI.
Cathomen, Toni   +5 more
core   +2 more sources

PCR-RFLP of mitochondrial DNA of swamp buffaloes in breeding station

open access: yesItalian Journal of Animal Science, 2010
Methods have been devised for detecting polymorphisms in the D-loop regions using the PCR followed by restriction enzyme digestion to reveal restriction fragment length polymorphism.
M. Kamonpatana   +6 more
doaj   +1 more source

Whole genome phylogeny for 21 Drosophila species using predicted 2b-RAD fragments [PDF]

open access: yesPeerJ, 2013
Type IIB restriction endonucleases are site-specific endonucleases that cut both strands of double-stranded DNA upstream and downstream of their recognition sequences.
Arun S. Seetharam, Gary W. Stuart
doaj   +2 more sources

Poly(ADP-ribosyl)ation is involved in the epigenetic control of TET1 gene transcription [PDF]

open access: yes, 2014
TET enzymes are the epigenetic factors involved in the formation of the Sixth DNA base 5-hydroxymethylcytosine, whose deregulation has been associated with tumorigenesis.
Bacalini, MARIA GIULIA   +9 more
core   +5 more sources

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