Results 191 to 200 of about 2,635,192 (296)

Centromeric DNA sequences in the pathogenic yeast Candida albicans are all different and unique

, 2004
Sanyal, Kaustuv, Baum, Mary, Carbon John
openalex   +2 more sources

Analyses of PCR products using DNA templates containing a consecutive deoxyinosine sequence [PDF]

, 2004
Kobayashi A
openalex   +1 more source

Peer Review #1 of "Time-calibrated phylogeny and full mitogenome sequence of the Galapagos sea lion (Zalophus wollebaeki) from scat DNA (v0.2)"

, 2023

openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

A Feature Engineering Method for Whole-Genome DNA Sequence with Nucleotide Resolution. [PDF]

Int J Mol Sci
Wang T, Cui Y, Sun T, Li H, Wang C, Hou Y, Wang M, Chen L, Wu J.   +8 more
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Embed-Search-Align: DNA sequence alignment using Transformer models. [PDF]

Bioinformatics
Holur P, Enevoldsen KC, Rajesh S, Mboning L, Georgiou T, Bouchard LS, Pellegrini M, Roychowdhury V.   +7 more
europepmc   +1 more source

Optimizing data intensive GPGPU computations for DNA sequence alignment

, 2009
Trapnell Cole, Schatz, Michael C.
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Building a neural network model to define DNA sequence specificity in V(D)J recombination. [PDF]

Nucleic Acids Res
Harris JC, Byrum JN, McKinney CB, Fairchild V, Wu DH, Fagg AH, Rodgers KK.   +6 more
europepmc   +1 more source