DNA sequence encodes the position of DNA supercoils
eLife, 2018 The three-dimensional organization of DNA is increasingly understood to play a decisive role in vital cellular processes. Many studies focus on the role of DNA-packaging proteins, crowding, and confinement in arranging chromatin, but structural ...
Sung Hyun Kim +5 more
doaj +1 more source
DNA Steganalysis Using Deep Recurrent Neural Networks
, 2018 Recent advances in next-generation sequencing technologies have facilitated the use of deoxyribonucleic acid (DNA) as a novel covert channels in steganography.
Bae, Ho +3 more
core +1 more source
Robust signatures in the current-voltage characteristics of DNA molecules oriented between two graphene nanoribbon electrodes [PDF]
, 2012 In this work we numerically calculate the electric current through three kinds of DNA sequences (telomeric, \lambda-DNA, and p53-DNA) described by different heuristic models.
Alberts B +10 more
core +3 more sources
An Analytical Study of DNA Sequence [PDF]
Al-Rafidain Journal of Computer Sciences and Mathematics, 2010 This paper contains a general introduction to Bioinformatics, theirs goals, objectives and their applied fields. Is then shed light on the real views of DNA of humans, some processors use mathematical and statistical analysis of the traditional purpose ...
Basil Thanoon, Fatima Hasan
doaj +1 more source
Sequence Dependence of Transcription Factor-Mediated DNA Looping [PDF]
, 2012 DNA is subject to large deformations in a wide range of biological processes. Two key examples illustrate how such deformations influence the readout of the genetic information: the sequestering of eukaryotic genes by nucleosomes, and DNA looping in ...
Barry +62 more
core +4 more sources
Human deoxyribonucleic acid (DNA) sequence [PDF]
المجلة العراقية للعلوم الاحصائية, 2011 The problem of finding genetic mutations is an issue of special importance for its relationship with genetics evolution of living organisms. In this paper we present three statistical methods proposed for the creation of genetic mutations, the first ...
doaj +1 more source
Understanding the sequence-dependence of DNA groove dimensions: implications for DNA interactions. [PDF]
PLoS ONE, 2010 BACKGROUND: The B-DNA major and minor groove dimensions are crucial for DNA-protein interactions. It has long been thought that the groove dimensions depend on the DNA sequence, however this relationship has remained elusive.
Christophe Oguey +2 more
doaj +1 more source
Position Effect Takes Precedence Over Target Sequence in Determination of Adenine Methylation Patterns in the Nuclear Genome of a Eukaryote, \u3cem\u3eTetrahymena thermophila\u3c/em\u3e [PDF]
, 1998 Approximately 0.8% of the adenine residues in the macronuclear DNA of the ciliated protozoan Tetrahymena thermophila are modified to N6-methyladenine. DNA methylation is site specific and the pattern of methylation is constant between clonal cell lines ...
Karrer, Kathleen M. +1 more
core +1 more source
From DNA sequence to application: possibilities and complications [PDF]
, 1999 The development of sophisticated genetic tools during the past 15 years have facilitated a tremendous increase of fundamental and application-oriented knowledge of lactic acid bacteria (LAB) and their bacteriophages.
A Bruttin +110 more
core +3 more sources
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source