Results 71 to 80 of about 25,600,830 (293)

A sequence-based 163plex microhaplotype assay for forensic DNA analysis

open access: yesFrontiers in Genetics, 2022
Novel genetic marker microhaplotype has led to an upsurge in forensic genetic research. This study established a 163 microhaplotype (MH) multiplex assay based on next-generation sequencing (NGS) and evaluated the assay’s performance and applicability ...
Ruiyang Tao   +6 more
doaj   +1 more source

BOOL-AN: A method for comparative sequence analysis and phylogenetic reconstruction [PDF]

open access: yes, 2009
A novel discrete mathematical approach is proposed as an additional tool for molecular systematics which does not require prior statistical assumptions concerning the evolutionary process.
Ittzés, Péter   +4 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Signal Processing Methods for Genomic Sequence Analysis [PDF]

open access: yes, 2007
Signal processing is the art of representing, transforming, analyzing, and manipulating signals. It deals with a wide range of signals, from speech and audio signals to images and video signals, and many others.
Yoon, Byung-Jun
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Evaluation of nucleosome forming potentials (NFPs) of forensically important STRs [PDF]

open access: yes, 2011
Degraded forensic samples have proved difficult to analyze and interpret. New analysis techniques are constantly being discovered and improved but researchers have overlooked the structural properties that could prevent or slow the process of degradation.
Thanakiatkrai, Phuvadol, Welch, Lindsey
core   +4 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

DNA Sequence Evolution through Integral Value Transformations [PDF]

open access: yes, 2011
In deciphering the DNA structures, evolutions and functions, Cellular Automata (CA) do have a significant role. DNA can be thought of as a one-dimensional multi-state CA, more precisely four states of CA namely A, T, C, and G which can be taken as ...
Pabitra Pal Choudhury   +4 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Some mathematical problems in genetics

open access: yesLietuvos Matematikos Rinkinys, 2007
After an introduction to genetic basics three problems are briefly discussed: microarray data analysis, a definition of noninformative DNA sequence, and genetic sequence alignment. More atention is paid to DNA sequence visualization and regularization of
Marijus Radavičius   +2 more
doaj   +1 more source

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