Results 51 to 60 of about 25,600,830 (293)

Improved Bayesian methods for detecting recombination and rate heterogeneity in DNA sequence alignments [PDF]

, 2011
DNA sequence alignments are usually not homogeneous. Mosaic structures may result as a consequence of recombination or rate heterogeneity. Interspecific recombination, in which DNA subsequences are transferred between different (typically viral or ...
Mantzaris, Alexander Vassilios, Husmeir, Dirk   +1 more
core   +3 more sources

Zinc finger recombinases with adaptable DNA sequence specificity [PDF]

, 2011
Site-specific recombinases have become essential tools in genetics and molecular biology for the precise excision or integration of DNA sequences. However, their utility is currently limited to circumstances where the sites recognized by the recombinase ...
Proudfoot, C., W. Marshall Stark, W Marshall Stark, Proudfoot Chris, Kolb, A.F., Proudfoot, Chris, Arlene L McPherson, Arlene L. McPherson, Kolb Andreas F., McPherson, A.L., McPherson Arlene L., Andreas F Kolb, McPherson, Arlene L, Proudfoot, Christopher, Andreas F. Kolb, Stark W. Marshall, Stark, W.M., Kolb, Andreas F, Stark, W Marshall, Chris Proudfoot   +19 more
core   +1 more source

A Situational Assessment of the Diagnostic Landscape and Organizational Readiness to Implement Next‐Generation Sequencing at Two Childhood Cancer Treatment Centers in Ghana

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Next‐generation sequencing (NGS) has emerged as a promising approach to improve diagnostic accuracy, but its feasibility in low‐ and middle‐income countries remains unknown. This study characterized the diagnostic landscape and assessed organizational readiness for NGS implementation at two childhood cancer treatment centers in Accra ...
Melissa Carvalho, Emmanuella Amoako, Nihad Salifu, Lily Gloria Tagoe, Yaw Bediako, Michelle Hermiston, Catherine Segbefia   +6 more
wiley   +1 more source

The mutational repertoire of uterine sarcomas and carcinosarcomas in a Brazilian cohort: A preliminary study [PDF]

Clinics
OBJECTIVES: The present study aimed to contribute to the catalog of genetic mutations involved in the carcinogenic processes of uterine sarcomas (USs) and carcinosarcomas (UCSs), which may assist in the accurate diagnosis of, and selection of treatment ...
Leonardo Tomiatti da Costa, Laura Gonzalez dos Anjos, Luciane Tsukamoto Kagohara, Giovana Tardin Torrezan, Claudia A. Andrade De Paula, Edmund Chada Baracat, Dirce Maria Carraro, Katia Candido Carvalho   +7 more
doaj   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

El Genoma bovino, métodos y resultados de su análisis

Revista Mvz Cordoba, 2011
El conocimiento del genoma de especies domésticas ha permitido la selección de características importantes para la producción y la aplicación de técnicas moleculares en mejoramiento genético.
Janeth Ortega, Luís García
doaj   +1 more source

A computer package for DNA sequence analysis

Nucleic Acids Research, 1984
We have developed a comprehensive software-hardware package for a CP/M based or other microcomputer which can perform four major functions in a molecular biology laboratory: (1) the acquisition and analysis of DNA sequence data, (2) word processing in the preparation of scientific manuscripts and figures, (3) general lab computation and data reduction,
Frederick R. Blattner, J. L. Schroeder
openaire   +4 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Analysis of mitochondrial DNA variation in the Egyptian population and its implications for forensic DNA analysis [PDF]

, 2010
The genetic sequence of human mitochondrial DNA (mtDNA) is of particular interest to forensic investigations involving human identification, as well as population genetics.
Gomaa, R
core  

Sequence specificity of single-stranded DNA-binding proteins:a novel DNA microarray approach [PDF]

, 2007
We have developed a novel DNA microarray-based approach for identification of the sequence-specificity of single-stranded nucleic-acid-binding proteins (SNABPs).
Estibeiro, Peter, Heinemann, U., Wear, M.A., Max, K.E., Morgan, Hugh P, Max, Klaas E A, Sadler, P.J., Morgan, H.P., Walkinshaw, M.D., Heinemann, Udo, Walkinshaw, Malcolm D, Wear, Martin A, Gallagher, Maurice P, Cubeddu, L., Sadler, Peter J, Estibeiro, P., Gallagher, M.P., Cubeddu, Liza   +17 more
core   +1 more source