Results 41 to 50 of about 874,379 (256)
Mesoscopic Model for Free Energy Landscape Analysis of DNA sequences [PDF]
, 2012 A mesoscopic model which allows us to identify and quantify the strength of binding sites in DNA sequences is proposed. The model is based on the Peyrard-Bishop-Dauxois model for the DNA chain coupled to a Brownian particle which explores the sequence ...
D. Prada-Gracia +8 more
core +3 more sources
Intramolecular integration within Moloney murine leukemia virus DNA [PDF]
, 1981 By screening a library of unintegrated, circular Moloney murine leukemia virus (M-MuLV) DNA cloned in lambda phage, we found that approximately 20% of the M-MuLV DNA inserts contained internal sequence deletions or inversions.
Baltimore, David +3 more
core
Analysis of DNA sequence variation within marine species using Beta-coalescents [PDF]
, 2011 We apply recently developed inference methods based on general coalescent processes to DNA sequence data obtained from various marine species. Several of these species are believed to exhibit so-called shallow gene genealogies, potentially due to extreme
Birkner, Matthias +2 more
core +3 more sources
Sequencing and Analysis of Neanderthal Genomic DNA [PDF]
Science, 2006 Our knowledge of Neanderthals is based on a limited number of remains and artifacts from which we must make inferences about their biology, behavior, and relationship to ourselves. Here, we describe the characterization of these extinct hominids from a new perspective, based on the development of a Neanderthal metagenomic library ...
Noonan, James P. +10 more
openaire +5 more sources
A Linear Algebra Approach to Fast DNA Mixture Analysis Using GPUs
, 2017 Analysis of DNA samples is an important step in forensics, and the speed of analysis can impact investigations. Comparison of DNA sequences is based on the analysis of short tandem repeats (STRs), which are short DNA sequences of 2-5 base pairs.
Helfer, Brian +4 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski +9 more
wiley +1 more source
The mutational repertoire of uterine sarcomas and carcinosarcomas in a Brazilian cohort: A preliminary study [PDF]
ClinicsOBJECTIVES: The present study aimed to contribute to the catalog of genetic mutations involved in the carcinogenic processes of uterine sarcomas (USs) and carcinosarcomas (UCSs), which may assist in the accurate diagnosis of, and selection of treatment ...
Leonardo Tomiatti da Costa +7 more
doaj +2 more sources
, 2014 The histone-DNA interaction in the nucleosome is a fundamental mechanism of genomic compaction and regulation, which remains largely unkown despite a growing structural knowledge of the complex.
Everaers, Ralf, Meyer, Sam
core +3 more sources
Seven-Cluster Structure of Larch Chloroplast Genome [PDF]
Журнал Сибирского федерального университета: Серия Биология, 2015 The paper presents a novel approach to study a nucleotide sequence structure with respect to the chloroplast genome DNA sequence analysis. A specific frequencies distribution pattern of the consecutive triple nucleotide fragments was identified in the ...
Michael G. Sadovsky +5 more
doaj +1 more source
Analysis of Sequence-Tagged-Connector Strategies for DNA Sequencing [PDF]
Genome Research, 1999 The BAC-end sequencing, or sequence-tagged-connector (STC), approach to genome sequencing involves sequencing the ends of BAC inserts to scatter sequence tags (STCs) randomly across the genome. Once any BAC or other large segment of DNA is sequenced to completion by conventional shotgun approaches, these STC tags can be used to identify a minimum ...
A F, Siegel +5 more
openaire +2 more sources