Results 101 to 110 of about 1,188,878 (324)
Molecular Oncology, EarlyView.Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa +13 more
wiley +1 more source
BMC BiologyBackground Plastids are usually involved in photosynthesis, but the secondary loss of this function is a widespread phenomenon in various lineages of algae and plants.
Kacper Maciszewski +6 more
doaj +1 more source
The use of exonuclease III for preparing single stranded DNA for use as a template in the chain terminator sequencing method [PDF]
, 1979 Andrew J.H. Smith
openalex +1 more source
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
Molecular Oncology, EarlyView.We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock +10 more
wiley +1 more source
Specific termination of RNA polymerase synthesis as a method of RNA and DNA sequencing [PDF]
, 1978 V.D. Axelrod +3 more
openalex +1 more source
Molecular Oncology, EarlyView.CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar +4 more
wiley +1 more source
DNA Linear Block Codes: Generation, Error-detection and Error-correction of DNA Codeword [PDF]
International Journal of Bioinformatics Intelligent Computing.
2022;1(2):103-126, 2019 In modern age, the increasing complexity of computation and communication technology is leading us towards the necessity of new paradigm. As a result, unconventional approach like DNA coding theory is gaining considerable attention. The storage capacity, information processing and transmission properties of DNA molecules stimulate the notion of DNA ...
arxiv
Molecular Oncology, EarlyView.Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy +12 more
wiley +1 more source
Beyond the Alphabet: Deep Signal Embedding for Enhanced DNA Clustering [PDF]
arXivThe emerging field of DNA storage employs strands of DNA bases (A/T/C/G) as a storage medium for digital information to enable massive density and durability. The DNA storage pipeline includes: (1) encoding the raw data into sequences of DNA bases; (2) synthesizing the sequences as DNA \textit{strands} that are stored over time as an unordered set; (3)
arxiv
Determination of the endpoints of partial deletion mutants of the attachment site of bacteriophage lambda by DNA sequencing [PDF]
, 1978 R. Wayne Davies +2 more
openalex +1 more source