Results 131 to 140 of about 1,871,571 (343)

DNA sequencing [PDF]

Proceedings of the Nutrition Society, 1996
openaire   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: large scale validity study [PDF]

, 2011
Rossa W. K. Chiu, Ranjit Akolekar, Yama W. L. Zheng, Miriam T Y Leung, Hao Sun, K.C. Allen Chan, Fiona M. F. Lun, Attie T. J. I. Go, Elizabeth T. Lau, William Wing Kee To, WC Leung, R. Y. K. Tang, Sidney K. C. Au-Yeung, Hugh Simon Lam, Y. Y. Kung, Xiaolang Zhang, J. M. G. van Vugt, Ryoko Minekawa, Mónica Tang, Jian Wang, Cees B.M. Oudejans, Tze Kin Lau, K. H. Nicolaides, Yuk Ming Dennis Lo   +23 more
openalex   +1 more source

SCOPE: A Normalization and Copy-Number Estimation Method for Single-Cell DNA Sequencing [PDF]

, 2020
Rujin Wang, D. Y. Lin, Yuchao Jiang
openalex   +1 more source

Evaluation of Tumor DNA Sequencing Results in Patients with Gastric and Gastroesophageal Junction Adenocarcinoma Stratified by TP53 Mutation Status [PDF]

, 2022
Anthony C. Wood, Yonghong Zhang, Qianxing Mo, Ling Cen, Jacques P. Fontaine, Sarah E. Hoffe, Jessica M. Frakes, Seán Dineen, José M. Pimiento, Christine M. Walko, Rutika Mehta   +10 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Distribution of Pathogenic Yeasts in Different Clinical Samples: Their Identification, Antifungal Susceptibility Pattern, and Cell Invasion Assays

Infection and Drug Resistance, 2020
Satish T Pote,1,2 Mahesh S Sonawane,1 Praveen Rahi,1 Sunil R Shah,3 Yogesh S Shouche,1 Milind S Patole,1 Madhuri R Thakar,2 Rohit Sharma1 1National Centre for Microbial Resource (NCMR), National Centre for Cell Science, NCCS Complex, S.P. Pune University,
Pote ST, Sonawane MS, Rahi P, Shah SR, Shouche YS, Patole MS, Thakar MR, Sharma R   +7 more
doaj  

DNA sequences [PDF]

Nature, 1992
openaire   +2 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Genetic differences among Moraxella bovis and Moraxella bovoculi isolates from infectious bovine keratoconjunctivitis (IBK) outbreaks in southern Brazil

Genetics and Molecular Biology
The objective of this study was to evaluate the genetic diversity of Moraxella bovis and Moraxella bovoculi bacteria isolated from infectious bovine keratoconjunctivitis (IBK) outbreaks in the state of Rio Grande do Sul, Brazil.
Helena Brocardo Comin, Robert Domingues, Emanuelle Baldo Gaspar, João Rodrigo Gil De Los Santos, Fernando Flores Cardoso   +4 more
doaj   +1 more source