Results 231 to 240 of about 1,741,840 (332)

Inferred clonal hematopoiesis from tumor DNA sequencing among men with prostate cancer: correlation with somatic tumor alterations and outcomes. [PDF]

Oncologist
Iranmanesh Y, Omar N, Rasouli A, Baras A, Pasca S, Gondek LP, Tsai HL, Denmeade SR, Carducci MA, Paller CJ, Markowski MC, Luo J, Eisenberger MA, Antonarakis ES, Marshall CH.   +14 more
europepmc   +1 more source

A nonsense mutation causing decreased levels of insulin receptor mRNA: detection by a simplified technique for direct sequencing of genomic DNA amplified by the polymerase chain reaction.

, 1990
Takashi Kadowaki, Hiroaki Kadowaki, Simeon I. Taylor   +2 more
openalex   +1 more source

DNA sequencing using differential extension with nucleotide subsets (DENS) [PDF]

, 1997
M. C. Raja, D. Zevin‐Sonkin, J. Shwartzburd, T. A. Rozovskaya, Ivan Sobolev, О. В. Чертков, Valarmathi Ramanathan, L. Lvovsky, Levy Ulanovsky   +8 more
openalex   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

DNA sequencing by hybridization: 100 bases read by a non-gel-based method.

, 1991
Žaklina Strezoska, Tatjana Paunesku, D Radosavljević, Ivan Labat, Radoje Drmanac, Radomir Crkvenjakov   +5 more
openalex   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

A regression based approach to phylogenetic reconstruction from multi-sample bulk DNA sequencing of tumors. [PDF]

PLoS Comput Biol
Schmidt H, Raphael BJ.
europepmc   +1 more source

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source

Whole Mitochondrial DNA Sequencing Using Fecal Samples from Domestic Dogs. [PDF]

Animals (Basel)
Sugasawa T, Nguyen KDM, Otani N, Maehara K, Kamiya F, Hirokawa A, Takemasa T, Watanabe K, Nishi T, Sato K, Shimmura S, Takahashi Y, Kanki Y.   +12 more
europepmc   +1 more source