Results 11 to 20 of about 35,316 (244)

Two-Domain DNA Strand Displacement [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2010
We investigate the computing power of a restricted class of DNA strand displacement structures: those that are made of double strands with nicks (interruptions) in the top strand.
Luca Cardelli
doaj   +6 more sources

Double Synchronization Based on DNA Strand Displacement Reaction [PDF]

open access: yesIEEE Access, 2020
As an important part of biological computing, DNA strand displacement technology is used to construct complex biochemical circuits. Reversible molecular chemical reactions are basic chemical reactions.
Junwei Sun   +3 more
doaj   +2 more sources

A novel bio-sensor based on DNA strand displacement. [PDF]

open access: yesPLoS ONE, 2014
DNA strand displacement technology performs well in sensing and programming DNA segments. In this work, we construct DNA molecular systems based on DNA strand displacement performing computation of logic gates.
Xiaolong Shi   +5 more
doaj   +4 more sources

Molecular Full Adder Based on DNA Strand Displacement [PDF]

open access: yesIEEE Access, 2020
A new method, namely DNA strand displacement (DSD), has recently emerged in the field of biocomputing. DSD uses the toehold domain as a starting point to cover the strand in the migration domain.
Wei Xiao   +4 more
doaj   +2 more sources

Timed Pulses in DNA Strand Displacement Reactions. [PDF]

open access: yesJ Am Chem Soc, 2023
Inspired by naturally occurring regulatory mechanisms that allow complex temporal pulse features with programmable delays in gene expression and biological pathways, we demonstrate here a strategy to achieve temporally programmed pulse output signals in DNA-based Strand Displacement Reactions (SDRs).
Bucci J   +4 more
europepmc   +4 more sources

DNA Strand-Displacement Temporal Logic Circuits. [PDF]

open access: yesJ Am Chem Soc, 2022
Molecular circuits capable of processing temporal information are essential for complex decision making in response to both the presence and history of a molecular environment. A particular type of temporal information that has been recognized to be important is the relative timing of signals.
Lapteva AP, Sarraf N, Qian L.
europepmc   +4 more sources

First passage time study of DNA strand displacement. [PDF]

open access: yesBiophys J, 2021
Abstract DNA strand displacement, where a single-stranded nucleic acid invades a DNA duplex, is pervasive in genomic processes and DNA engineering applications. The kinetics of strand displacement have been studied in bulk; however, the kinetics of the underlying strand exchange were obfuscated by a slow bimolecular association step ...
Broadwater DWB, Cook AW, Kim HD.
europepmc   +7 more sources

Four-Analog Computation Based on DNA Strand Displacement [PDF]

open access: yesACS Omega, 2017
Chengye Zou   +5 more
doaj   +2 more sources

Natural and Modified Oligonucleotide Sequences Show Distinct Strand Displacement Kinetics and These Are Affected Further by Molecular Crowders

open access: yesBiomolecules, 2022
DNA and RNA strand exchange is a process of fundamental importance in biology. Herein, we used a FRET-based assay to investigate, for the first time, the stand exchange kinetics of natural DNA, natural RNA, and locked nucleic acid (LNA)-modified DNA ...
Ivana Domljanovic   +4 more
doaj   +1 more source

DNA Strand Displacement Driven by Host-Guest Interactions. [PDF]

open access: yesJ Am Chem Soc, 2022
Base-pair-driven toehold-mediated strand displacement (BP-TMSD) is a fundamental concept employed for constructing DNA machines and networks with a gamut of applications─from theranostics to computational devices. To broaden the toolbox of dynamic DNA chemistry, herein, we introduce a synthetic surrogate termed host-guest-driven toehold-mediated strand
Kankanamalage DVDW   +9 more
europepmc   +3 more sources

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