Results 21 to 30 of about 37,201 (270)
8-Bit Adder and Subtractor with Domain Label Based on DNA Strand Displacement [PDF]
Molecules, 2018 DNA strand displacement, which plays a fundamental role in DNA computing, has been widely applied to many biological computing problems, including biological logic circuits.
Weixuan Han, Changjun Zhou
doaj +2 more sources
DNA dynamics and computation based on toehold-free strand displacement
Nature Communications, 2021 Synthetic DNA constructs can to used to recognise and respond to input signals. Here the authors present complex DNA nanostructures with toehold-free strand displacement for generation of ON/OFF switches and Boolean gates.
Hong Kang +5 more
doaj +2 more sources
A Coupled Reconfiguration Mechanism for Single-Stranded DNA Strand Displacement Systems [PDF]
, 2022 DNA Strand Displacement (DSD) systems model basic reaction rules, such as toehold-mediated strand displacement and 4-way branch migration, that modify complexes of bound DNA strands.
Condon, Anne, Johnson, Hope Amber
core +4 more sources
DNA Strand-Displacement Timer Circuits
ACS Synthetic Biology, 2016 Chemical circuits can coordinate elaborate sequences of events in cells and tissues, from the self-assembly of biological complexes to the sequence of embryonic development.
Dylan Howie (3225549) +5 more
core +3 more sources
Modular DNA strand-displacement controllers for directing material expansion [PDF]
Nature Communications, 2018 Materials which change shape in response to a trigger are of interest for soft robotics and targeted therapeutic delivery. Here, the authors report on the development of DNA-crosslinked hydrogels which can expand upon the detection of different ...
Joshua Fern, Rebecca Schulman
doaj +2 more sources
DNA Strand-Displacement Temporal Logic Circuits. [PDF]
J Am Chem Soc, 2022 Molecular circuits capable of processing temporal information are essential for complex decision making in response to both the presence and history of a molecular environment. A particular type of temporal information that has been recognized to be important is the relative timing of signals.
Lapteva AP, Sarraf N, Qian L.
europepmc +4 more sources
Mechanism of strand displacement synthesis by DNA replicative polymerases
Nucleic Acids Research, 2016 Replicative holoenzymes exhibit rapid and processive primer extension DNA synthesis, but inefficient strand displacement DNA synthesis. We investigated the bacteriophage T4 and T7 holoenzymes primer extension activity and strand displacement activity on ...
Bensimon, David +6 more
core +4 more sources
Logical Reasoning Based on DNA Strand Displacement [PDF]
Jisuanji kexue, 2022 A computational model for logical reasoning is proposed based on DNA strand displacement reactions.Firstly,this way does not rely on fluorescent labeling or other DNA experimental technique.The corresponding relationship between the concentration change ...
WU Li-bo, HUANG Yu-fang
doaj +1 more source
First passage time study of DNA strand displacement. [PDF]
Biophys J, 2021 Abstract DNA strand displacement, where a single-stranded nucleic acid invades a DNA duplex, is pervasive in genomic processes and DNA engineering applications. The kinetics of strand displacement have been studied in bulk; however, the kinetics of the underlying strand exchange were obfuscated by a slow bimolecular association step ...
Broadwater DWB, Cook AW, Kim HD.
europepmc +7 more sources
DNA Strand Displacement Driven by Host-Guest Interactions. [PDF]
J Am Chem Soc, 2022 Base-pair-driven toehold-mediated strand displacement (BP-TMSD) is a fundamental concept employed for constructing DNA machines and networks with a gamut of applications─from theranostics to computational devices. To broaden the toolbox of dynamic DNA chemistry, herein, we introduce a synthetic surrogate termed host-guest-driven toehold-mediated strand
Kankanamalage DVDW +9 more
europepmc +3 more sources