In vivo occupancy of mitochondrial single-stranded DNA binding protein supports the strand displacement mode of DNA replication. [PDF]
PLoS Genetics, 2014 Mitochondrial DNA (mtDNA) encodes for proteins required for oxidative phosphorylation, and mutations affecting the genome have been linked to a number of diseases as well as the natural ageing process in mammals.
Javier Miralles Fusté +8 more
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DNA Strand-Displacement Temporal Logic Circuits. [PDF]
J Am Chem Soc, 2022 Molecular circuits capable of processing temporal information are essential for complex decision making in response to both the presence and history of a molecular environment. A particular type of temporal information that has been recognized to be important is the relative timing of signals.
Lapteva AP, Sarraf N, Qian L.
europepmc +4 more sources
Logical Reasoning Based on DNA Strand Displacement [PDF]
Jisuanji kexue, 2022 A computational model for logical reasoning is proposed based on DNA strand displacement reactions.Firstly,this way does not rely on fluorescent labeling or other DNA experimental technique.The corresponding relationship between the concentration change ...
WU Li-bo, HUANG Yu-fang
doaj +1 more source
First passage time study of DNA strand displacement. [PDF]
Biophys J, 2021 Abstract DNA strand displacement, where a single-stranded nucleic acid invades a DNA duplex, is pervasive in genomic processes and DNA engineering applications. The kinetics of strand displacement have been studied in bulk; however, the kinetics of the underlying strand exchange were obfuscated by a slow bimolecular association step ...
Broadwater DWB, Cook AW, Kim HD.
europepmc +7 more sources
Catalytic-Assembly of Nanoparticle Supercrystals by a pH-Controlled DNA Strand-Displacement Circuit. [PDF]
JACS AuLiu X +7 more
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Design of hidden thermodynamic driving for non-equilibrium systems via mismatch elimination during DNA strand displacement. [PDF]
Nat Commun, 2020 Haley NEC +6 more
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DNA Strand Displacement Driven by Host-Guest Interactions. [PDF]
J Am Chem Soc, 2022 Base-pair-driven toehold-mediated strand displacement (BP-TMSD) is a fundamental concept employed for constructing DNA machines and networks with a gamut of applications─from theranostics to computational devices. To broaden the toolbox of dynamic DNA chemistry, herein, we introduce a synthetic surrogate termed host-guest-driven toehold-mediated strand
Kankanamalage DVDW +9 more
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Biomolecules, 2022 DNA and RNA strand exchange is a process of fundamental importance in biology. Herein, we used a FRET-based assay to investigate, for the first time, the stand exchange kinetics of natural DNA, natural RNA, and locked nucleic acid (LNA)-modified DNA ...
Ivana Domljanovic +4 more
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Kinetics of DNA Strand Displacement Systems with Locked Nucleic Acids. [PDF]
J Phys Chem B, 2017 Olson X +4 more
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DNA strand displacement, strand annealing and strand swapping by the Drosophila Bloom's syndrome helicase [PDF]
Nucleic Acids Research, 2007 Genetic analysis of the Drosophila Bloom's syndrome helicase homolog (mus309/DmBLM) indicates that DmBLM is required for the synthesis-dependent strand annealing (SDSA) pathway of homologous recombination. Here we report the first biochemical study of DmBLM.
Brian T. Weinert, Donald C. Rio
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