Results 231 to 240 of about 113,306 (267)

[DNA topoisomerase inhibitor].

Gan to kagaku ryoho. Cancer & chemotherapy, 1992
CPT-11 and Topotecan are a new semisynthetic derivative of CPT, and have been shown to inhibit DNA topoisomerase I and to have a strong antitumor activity with low toxicity against murine tumor. On the other hard, the new antitumor compounds, NC-190 and IST-622 have been shown to inhibit DNA topoisomerase II, and the clinical study are currently under ...
T, Sugiura, Y, Ariyoshi
openaire   +1 more source

DNA topoisomerases

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1998
openaire   +2 more sources

Eukaryotic DNA topoisomerases I

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1995
M, Gupta, A, Fujimori, Y, Pommier
openaire   +2 more sources

Inhibitors of DNA topoisomerases

Biochemistry, 1988
K, Drlica, R J, Franco
openaire   +2 more sources

DNA topoisomerases

Current Opinion in Structural Biology, 1991
openaire   +1 more source

Targeting DNA topoisomerase II in cancer chemotherapy

Nature Reviews Cancer, 2009
John L. Nitiss
exaly  

All tangled up: how cells direct, manage and exploit topoisomerase function

Nature Reviews Molecular Cell Biology, 2011
Seychelle M Vos, James M Berger
exaly  

DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition

Chemical Reviews, 2009
Yves Pommier
exaly  

A human 5′-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage

Nature, 2009
Felipe Cortés Ledesma, Kay Osborn, Keith W Caldecott   +2 more
exaly  

DNA topoisomerase II and its growing repertoire of biological functions

Nature Reviews Cancer, 2009
John L. Nitiss
exaly