Results 211 to 220 of about 1,464,924 (278)

From Nucleobases to Bioactive NHC‐Based Gold and Silver Complexes With Anticancer and Antiviral Activity

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
Herein, we reported the design and synthesis of a novel series of N‐heterocyclic carbene (NHC) complexes originated from the imidazole ring of guanine and guanosine and with different counterions (iodide, acetate, and aminoacidate). The evaluation of the biological activities, that is anticancer and antiviral, indicated L2AuOAc as the best complex ...
Domenico Iacopetta, Jessica Ceramella, Paola Checconi, Flavio Frezza, Maria Marra, Annaluisa Mariconda, Assunta D’Amato, Alessia Catalano, Stefano Aquaro, Pasquale Longo, Maria Stefania Sinicropi   +10 more
wiley   +1 more source

Topoisomerases regulate alternative transcription start site selection in yeast. [PDF]

G3 (Bethesda)
Elgood Hunt E, Vivori C, Albihlal WS, van Werven FJ.   +3 more
europepmc   +1 more source

Chromosome segregation in a minimal bacterial cell driven by SMC protein complexes. [PDF]

Protein Sci
Maytin AK, Gilbert BR, Luthey-Schulten Z.   +2 more
europepmc   +1 more source

Bacterial type II topoisomerases cleave DNA in a species-specific manner. [PDF]

Nucleic Acids Res
Morgan IL, Jian JY, Armenia JF, Osheroff N, Neuman KC.   +4 more
europepmc   +1 more source

Topoisomerase inhibitors in cervical cancer: mechanistic insights and therapeutic strategies. [PDF]

Mol Med
Reddy Y, Pai P, Das I, Nayak S, D'Souza NV, Shetty MG, Sundara BK.   +6 more
europepmc   +1 more source

Involvement of DNA topoisomerases and DNA topoisomerase inhibitors in the induction of leukemia cell differentiation

Annals of Oncology, 1994
openaire   +2 more sources

Direct trapping of the transport-segment DNA by the central domain of type IIA topoisomerases. [PDF]

Sci Adv
Xin Y, Xian R, Liu C, Zhang O, Rao Z, Li X, Chen Y.   +6 more
europepmc   +1 more source

Networked salt-bridges mediate magnesium-dependent conformational dynamics and functional regulation in type IA topoisomerases. [PDF]

Nat Commun
Seol Y, Tse-Dinh YC, Neuman KC.
europepmc   +1 more source

Barettin Suppresses Pancreatic Ductal Adenocarcinoma Proliferation via Topoisomerase IIα Inhibition. [PDF]

Mar Drugs
Seekins CA, Archuleta MR, Evans AE, Podgorski J, Carr JE, Kaleeswaran V, Nguyen KB, Flowers ME, Hulme C, Vanderah TW, Cárdenas P, Streicher JM, Lee NY, Cartmell C.   +13 more
europepmc   +1 more source

Novel Bacterial Topoisomerase Inhibitors: A New Front in an Old War. [PDF]

J Mol Biol
Mann CA, Dewar JM, Osheroff N.
europepmc   +1 more source