Regulatory transposable elements in the encyclopedia of DNA elements
Nature Communications, 2023 Transposable elements (TEs) comprise ~50% of our genome, but knowledge of how TEs affect genome evolution remains incomplete. Leveraging ENCODE4 data, we provide the most comprehensive study to date of TE contributions to the regulatory genome.
Alan Y. Du +4 more
doaj +5 more sources
Transposable Elements as a Source of Novel Repetitive DNA in the Eukaryote Genome [PDF]
Cells, 2022 The impact of transposable elements (TEs) on the evolution of the eukaryote genome has been observed in a number of biological processes, such as the recruitment of the host’s gene expression network or the rearrangement of genome structure. However, TEs
Michelle Louise Zattera +1 more
semanticscholar +5 more sources
Transposable Elements: No More 'Junk DNA' [PDF]
Genomics & Informatics, 2012 Since the advent of whole-genome sequencing, transposable elements (TEs), just thought to be 'junk' DNA, have been noticed because of their numerous copies in various eukaryotic genomes.
Yun-Ji Kim, Jungnam Lee, Kyudong Han
doaj +4 more sources
DNA on the move: mechanisms, functions and applications of transposable elements
FEBS Open Bio, 2023 Transposons are mobile genetic elements that have invaded all domains of life by moving between and within their host genomes. Due to their mobility (or transposition), transposons facilitate horizontal gene transfer in bacteria and foster the evolution ...
Michael Schmitz, Irma Querques
doaj +4 more sources
Proliferation of Regulatory DNA Elements Derived from Transposable Elements in the Maize Genome [PDF]
Plant Physiology, 2018 Genomic regions free of nucleosomes, which are hypersensitive to DNase I digestion, are known as DNase I hypersensitive sites (DHSs) and frequently contain cis-regulatory DNA elements. To investigate their prevalence and characteristics in maize (Zea mays), we developed high-resolution genome-wide DHS maps using a modified DNase-seq technique.
Hainan Zhao +6 more
semanticscholar +4 more sources
Satellite DNA and Transposable Elements in Seabuckthorn ( Hippophae rhamnoides ), a Dioecious Plant with Small Y and Large X Chromosomes [PDF]
Genome Biology and Evolution, 2017 Seabuckthorn (Hippophae rhamnoides) is a dioecious shrub commonly used in the pharmaceutical, cosmetic, and environmental industry as a source of oil, minerals and vitamins.
Janka Puterová +8 more
openalex +2 more sources
Widespread contribution of transposable elements to the rewiring of mammalian 3D genomes
Nature Communications, 2023 Here the authors show transposable elements, formerly considered junk DNA, are a source of CTCF binding sites that contribute to species-specific 3D-genome structure, and may impact gene regulation during the course of mammalian evolution.
Mayank N. K. Choudhary +4 more
doaj +2 more sources
Transposable Elements, Inflammation, and Neurological Disease. [PDF]
Frontiers in Neurology, 2019 Transposable Elements (TE) are mobile DNA elements that can replicate and insert themselves into different locations within the host genome. Their propensity to self-propagate has a myriad of consequences and yet their biological significance is not well-
Macia, Angela +2 more
core +2 more sources
Transposable elements as key regulators of placental development. [PDF]
Vavilovskii Zhurnal Genet SelektsiiTransposable elements (TEs), comprising over one-third of the human genome, play a crucial role in its evolution, serving as a significant source of regulatory sequences. Under normal circumstances, their activity is tightly controlled by DNA methylation
Zhilkina MA, Tolmacheva EN, Vasilyev SA.
europepmc +2 more sources
Extrachromosomal Circular DNA and Transposable Elements in Type 2 Diabetes. [PDF]
Int J Mol SciMoya-Valera C +4 more
europepmc +2 more sources