Results 1 to 10 of about 256,749 (282)
Regulatory transposable elements in the encyclopedia of DNA elements [PDF]
Nature Communications, 2023 Transposable elements (TEs) comprise ~50% of our genome, but knowledge of how TEs affect genome evolution remains incomplete. Leveraging ENCODE4 data, we provide the most comprehensive study to date of TE contributions to the regulatory genome.
Alan Y. Du +4 more
doaj +7 more sources
Transposable Elements: No More 'Junk DNA' [PDF]
Genomics & Informatics, 2012 Since the advent of whole-genome sequencing, transposable elements (TEs), just thought to be 'junk' DNA, have been noticed because of their numerous copies in various eukaryotic genomes.
Yun-Ji Kim, Jungnam Lee, Kyudong Han
doaj +5 more sources
Proliferation of Regulatory DNA Elements Derived from Transposable Elements in the Maize Genome1[OPEN] [PDF]
Plant Physiology, 2018 Genomic regions free of nucleosomes, which are hypersensitive to DNase I digestion, are known as DNase I hypersensitive sites (DHSs) and frequently contain cis-regulatory DNA elements. To investigate their prevalence and characteristics in maize (Zea mays), we developed high-resolution genome-wide DHS maps using a modified DNase-seq technique.
Hainan Zhao +6 more
semanticscholar +4 more sources
Zisupton--a novel superfamily of DNA transposable elements recently active in fish. [PDF]
Molecular Biology and Evolution, 2012 Transposable elements are widespread mobile DNA sequences able to integrate into new locations within genomes. Through transposition and recombination, they significantly contribute to genome plasticity and evolution.
A. Böhne +6 more
semanticscholar +6 more sources
Small RNAs, DNA methylation and transposable elements in wheat [PDF]
BMC Genomics, 2010 Background More than 80% of the wheat genome is composed of transposable elements (TEs). Since active TEs can move to different locations and potentially impose a significant mutational load, their expression is suppressed in the genome via small non ...
Matvienko Marta +7 more
doaj +9 more sources
Changes in global gene expression in response to chemical and genetic perturbation of chromatin structure. [PDF]
PLoS ONE, 2011 DNA methylation is important for controlling gene expression in all eukaryotes. Microarray analysis of mutant and chemically-treated Arabidopsis thaliana seedlings with reduced DNA methylation revealed an altered gene expression profile after treatment ...
Karen Hudson +3 more
doaj +12 more sources
Regulation of transposable elements by DNA modifications [PDF]
Nature Reviews Genetics, 2019 Maintenance of genome stability requires control over the expression of transposable elements (TEs), whose activity can have substantial deleterious effects on the host. Chemical modification of DNA is a commonly used strategy to achieve this, and it has long been argued that the emergence of 5-methylcytosine (5mC) in many species was driven by the ...
Özgen Deniz, J. Frost, M. Branco
semanticscholar +4 more sources
Mobilization of DNA transposable elements from lentiviral vectors [PDF]
Mobile Genetic Elements, 2011 With the Sleeping Beauty (SB) DNA transposon, a reconstructed Tc1/mariner element, as the driving force, DNA transposable elements have emerged as new gene delivery vectors with therapeutic potential. The bipartite transposon vector system consists of a transposon vector carrying the transgene and a source of the transposase that catalyzes transposon ...
R. Bak, J. Mikkelsen
semanticscholar +5 more sources
DNA demethylases target promoter transposable elements to positively regulate stress responsive genes in Arabidopsis [PDF]
Genome Biology, 2014 BackgroundDNA demethylases regulate DNA methylation levels in eukaryotes. Arabidopsis encodes four DNA demethylases, DEMETER (DME), REPRESSOR OF SILENCING 1 (ROS1), DEMETER-LIKE 2 (DML2), and DML3.
T. Le +11 more
semanticscholar +4 more sources
Author Correction: Regulation of transposable elements by DNA modifications [PDF]
Nature Reviews Genetics, 2019 The originally published article contained an error in Figure 2a: for the left side of the figure part (showing piRNA-directed DNA methylation of mouse transposable elements), DNMT3A/B should have been DNMT3C. The article has now been corrected online.
Özgen Deniz, J. Frost, M. Branco
semanticscholar +3 more sources