Transposable Elements: No More 'Junk DNA' [PDF]
Genomics & Informatics, 2012 Since the advent of whole-genome sequencing, transposable elements (TEs), just thought to be 'junk' DNA, have been noticed because of their numerous copies in various eukaryotic genomes.
Yun-Ji Kim, Jungnam Lee, Kyudong Han
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Regulatory transposable elements in the encyclopedia of DNA elements
Nature Communications, 2023 Transposable elements (TEs) comprise ~50% of our genome, but knowledge of how TEs affect genome evolution remains incomplete. Leveraging ENCODE4 data, we provide the most comprehensive study to date of TE contributions to the regulatory genome.
Alan Y. Du +4 more
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Zisupton--A Novel Superfamily of DNA Transposable Elements Recently Active in Fish [PDF]
Molecular Biology and Evolution, 2011 Transposable elements are widespread mobile DNA sequences able to integrate into new locations within genomes. Through transposition and recombination, they significantly contribute to genome plasticity and evolution.
Astrid Böhne +6 more
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DNA demethylases target promoter transposable elements to positively regulate stress responsive genes in Arabidopsis [PDF]
Genome Biology, 2014 BackgroundDNA demethylases regulate DNA methylation levels in eukaryotes. Arabidopsis encodes four DNA demethylases, DEMETER (DME), REPRESSOR OF SILENCING 1 (ROS1), DEMETER-LIKE 2 (DML2), and DML3.
Tuan-Ngoc Le +11 more
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Widespread contribution of transposable elements to the rewiring of mammalian 3D genomes
Nature Communications, 2023 Here the authors show transposable elements, formerly considered junk DNA, are a source of CTCF binding sites that contribute to species-specific 3D-genome structure, and may impact gene regulation during the course of mammalian evolution.
Mayank N. K. Choudhary +4 more
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Role of H1 and DNA methylation in selective regulation of transposable elements during heat stress [PDF]
New Phytologist, 2020 Summary Heat‐stressed Arabidopsis plants release heterochromatin‐associated transposable element (TE) silencing, yet it is not accompanied by major reductions of epigenetic repressive modifications.
Shujing Liu +5 more
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Expression of DNA transposable elements during nervous system development [PDF]
Mobile Genetic Elements, 2011 Transposable elements (retrotransposons and DNA transposons) comprise a large proportion of animal genomes, for example 20% in D. melanogaster, 36% in X. tropicalis and 45% in humans.
Fernando Faunes +2 more
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Transposable Elements, Inflammation, and Neurological Disease. [PDF]
Frontiers in Neurology, 2019 Transposable Elements (TE) are mobile DNA elements that can replicate and insert themselves into different locations within the host genome. Their propensity to self-propagate has a myriad of consequences and yet their biological significance is not well-
Macia, Angela +2 more
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Full-length autonomous transposable elements are preferentially targeted by expression-dependent forms of RNA-directed DNA methylation [PDF]
Genome Biology, 2016 BackgroundChromatin modifications such as DNA methylation are targeted to transposable elements by small RNAs in a process termed RNA-directed DNA methylation (RdDM). In plants, canonical RdDM functions through RNA polymerase IV to reinforce pre-existing
Kaushik Panda +5 more
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Sex and the TEs: transposable elements in sexual development and function in animals
Mobile DNA, 2019 Transposable elements are endogenous DNA sequences able to integrate into and multiply within genomes. They constitute a major source of genetic innovations, as they can not only rearrange genomes but also spread ready-to-use regulatory sequences able to
Corentin Dechaud +3 more
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